ChemicalBook > CAS DataBase List > 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

Product Name: 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
CAS No.: 405057-75-2
Chemical Name: 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
Synonyms: 1-Cbz-4-methylaminopieridine;1-Cbz-4-methylaminopiperidine;1-N-CBZ-4-(METHYLAMINO)PIPERIDINE;Benzyloxycarbonyl)-4-methylaminopiperidine;benzyl4-(methylamino)piperidine-1-carboxylate;1-(Benzyloxycarbonyl)-4-MethylaMinopiperidine;4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;benzyl 4-(methylamino)piperidine-1-carboxylate hydrochloride;4-(Methylamino)-1-piperidinecarboxylic acid phenylmethyl ester;1-Piperidinecarboxylic acid, 4-(methylamino)-, phenylmethyl ester
CBNumber: CB1167023
Molecular Formula: C14H20N2O2
Formula Weight: 248.32
MOL File: 405057-75-2.mol

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4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER Property

storage temp.: Sealed in dry,Room Temperature
Appearance: Light yellow to yellow Liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B194180
Product name: Benzyl4-(Methylamino)piperidine-1-carboxylate
Packaging: 500mg
Price: $125
Updated: 2021/12/16

TRC

Product number: B194180
Product name: Benzyl4-(Methylamino)piperidine-1-carboxylate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0149068
Product name: 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
Purity: 95.00%
Packaging: 5G
Price: $4966.5
Updated: 2021/12/16

AK Scientific

Product number: W6098
Product name: 1-Cbz-4-Methylaminopieridine
Packaging: 1g
Price: $141
Updated: 2021/12/16

Chemenu

Product number: CM180407
Product name: 1-Cbz-4-Methylaminopieridine
Purity: 95%
Packaging: 5g
Price: $219
Updated: 2021/12/16

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4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER Chemical Properties,Usage,Production

Synthesis

19099-93-5

593-51-1

405057-75-2

GENERAL STEPS: To a suspension of 1-(benzyloxycarbonyl)piperidin-4-one (4 g, 17.16 mmol), methylamine hydrochloride (1.95 g, 18.88 mmol) and sodium triacetoxyborohydride (5.09 g, 24.02 mmol) in 1,2-dichloroethane (46 mL) was added acetic acid (0.8 mL, 12.7 mmol). The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate (50 mL) and the organic layer was extracted with dichloromethane (3 x 40 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford the crude product 1-(benzyloxycarbonyl)-4-(methylamino)piperidine (4 g, 100% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.31-7.35 (m, 5H), 5.12 (s, 2H), 4.13 (s, 2H), 3.72 (s, 3H), 2.86 (t, J = 10Hz, 1H), 2.56-2.63 (m, 1H), 2.48 (s, 3H), 2.12 (s, 3H) , 1.91 (s, 1H), 1.22-1.39 (m, 2H).

References

[1] Patent: WO2009/76387, 2009, A1. Location in patent: Page/Page column 40

4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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405057-75-2, 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTERRelated Search:

4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONOBENZYL ESTER 4-METHYLAMINO-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 2-METHYL ESTER 4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 4-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PIPERIDINE-1,4-DICARBOXYLIC ACID MONOBENZYL ESTER BENZYL 4-(4-OXOPIPERIDIN-1-YL)PIPERIDINE-1-CARBOXYLATE L-N-(4'-N-CBZ-PIPERIDINO)PROLINE 4-ETHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 4-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 4-BENZYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER (1-CBZ-PIPERIDIN-4-YL-AZETIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER BENZYL-4-(TERT-BUTOXYCARBONYLAMINO)PIPERIDINE-1-CARBOXYLATE

1-N-CBZ-4-(METHYLAMINO)PIPERIDINE

4-METHYLAMINO-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER

1-Cbz-4-methylaminopiperidine

1-Cbz-4-methylaminopiperidine 4-Methylamino-piperidine-1-carboxylic acid benzyl ester 1-piperidinecarboxylic acid,4-(methylamino)-,phenylmethyl ester

1-Cbz-4-methylaminopieridine

benzyl4-(methylamino)piperidine-1-carboxylate

Benzyloxycarbonyl)-4-methylaminopiperidine

benzyl 4-(methylamino)piperidine-1-carboxylate hydrochloride

1-(Benzyloxycarbonyl)-4-MethylaMinopiperidine

4-(Methylamino)-1-piperidinecarboxylic acid phenylmethyl ester

1-Piperidinecarboxylic acid, 4-(methylamino)-, phenylmethyl ester

405057-75-2