ChemicalBook > CAS DataBase List > TETRAMETHYL-1,3-CYCLOBUTANEDIONE

TETRAMETHYL-1,3-CYCLOBUTANEDIONE

Product Name
TETRAMETHYL-1,3-CYCLOBUTANEDIONE
CAS No.
933-52-8
Chemical Name
TETRAMETHYL-1,3-CYCLOBUTANEDIONE
Synonyms
NSC 72172;NSC 46472;Dimethylkene dimer;RARECHEM AQ C4 0041;TIMTEC-BB SBB008408;DIMETHYL KETENE DIMER;Tetramethylcyclobutenedione;Tetramethylcyclobuta-1,3-dione;[Precursor to DiMethyl Ketene];TETRAMETHYLCYCLOBUTANE-1,3-DIONE
CBNumber
CB1177783
Molecular Formula
C8H12O2
Formula Weight
140.18
MOL File
933-52-8.mol
More
Less

TETRAMETHYL-1,3-CYCLOBUTANEDIONE Property

Melting point:
114-116 °C(lit.)
Boiling point:
95-159 °C750 mm Hg(lit.)
Density 
1.0373 (rough estimate)
refractive index 
1.4580 (estimate)
Flash point:
120-122°C/150mm
storage temp. 
Sealed in dry,Room Temperature
solubility 
It is soluble in chloroform.
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C8H12O2/c1-7(2)5(9)8(3,4)6(7)10/h1-4H3
InChIKey
RGCDVHNITQEYPO-UHFFFAOYSA-N
SMILES
C1(=O)C(C)(C)C(=O)C1(C)C
CAS DataBase Reference
933-52-8(CAS DataBase Reference)
EPA Substance Registry System
1,3-Cyclobutanedione, 2,2,4,4-tetramethyl- (933-52-8)
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
GU1775000
TSCA 
Yes
HS Code 
2914290090
Hazardous Substances Data
933-52-8(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T21008
Product name
Tetramethyl-1,3-cyclobutanedione
Purity
99%
Packaging
5g
Price
$59.18
Updated
2025/07/31
TCI Chemical
Product number
D0258
Product name
Tetramethyl-1,3-cyclobutanedione [Precursor to Dimethyl Ketene]
Purity
>99.0%(GC)
Packaging
5g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
D0258
Product name
Tetramethyl-1,3-cyclobutanedione [Precursor to Dimethyl Ketene]
Purity
>99.0%(GC)
Packaging
25g
Price
$143
Updated
2025/07/31
TRC
Product number
T204598
Product name
Tetramethyl-1,3-Cyclobutanedione
Packaging
50mg
Price
$45
Updated
2021/12/16
GFS CHEMICALS
Product number
73162
Product name
TETRAMETHYLCYCLOBUTADIONE
Packaging
25g
Price
$81.95
Updated
2021/12/16
More
Less

TETRAMETHYL-1,3-CYCLOBUTANEDIONE Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

Tetramethyl-1,3-cyclobutanedione is used as a chemical for life science research. It is also used to make other chemical, as well as an chemical and organic intermediate.

Synthesis Reference(s)

Canadian Journal of Chemistry, 50, p. 3923, 1972 DOI: 10.1139/v72-619

Purification Methods

Crystallise the dione from *C6H6 and dry it in vacuo over P2O5 in an Abderhalden pistol. [Beilstein 7 III 3234, 7 IV 2004.]

TETRAMETHYL-1,3-CYCLOBUTANEDIONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

TETRAMETHYL-1,3-CYCLOBUTANEDIONE Suppliers

Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
991
Advantage
58
Zhejiang zetian fine chemical co. LTD
Tel
0571-87322520 18957127338
Fax
QQ:800182836
Email
sales@zetchem.com
Country
China
ProdList
445
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Arbor Chemical Co., Ltd.
Tel
021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
896
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1490
Advantage
62
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3921
Advantage
50
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Guangzhou Jhd Chemical Reagent Co., Ltd.
Tel
020-84383047
Fax
020-84380294
Email
sales@jhd.com.cn
Country
China
ProdList
9186
Advantage
65
LinkChem Technology Co., Ltd.
Tel
021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
2998
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-(0)57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Xenoah Pharmaceutical Inc.
Tel
0512-6956-1983
Email
info@xenoah.com
Country
China
ProdList
296
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Shanghai Tube Pharmaceutical Co., Ltd.
Tel
021-54338626 18017892860
Fax
021-54338626
Email
sales@tubepharm.com
Country
China
ProdList
2572
Advantage
58
Hefei Molake Biotechnology Co., Ltd.
Tel
0551-66336380 18956014586
Fax
055166336380
Email
983438788@qq.com
Country
China
ProdList
2297
Advantage
58
Hangzhou Xinbaisi Biomedical Co., Ltd.
Tel
13325818654
Fax
057188737015
Email
zhsj@synbestech.com
Country
China
ProdList
249
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-55055611 18137792234
Fax
QQ:3002694073
Email
3002694073@qq.com
Country
China
ProdList
9987
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652,+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Shanxi Xuanran Import and Export Trade Co., Ltd.
Tel
+8617735180244
Email
mike_yan@xuanranglobal.com
Country
CHINA
ProdList
4017
Advantage
58
Guangdong Wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886766 13927870850
Fax
0751-2886756
Email
3001267247@qq.com
Country
China
ProdList
9941
Advantage
58
Shandong chuangyingchemical Co., Ltd.
Tel
18853181302
Email
sale@chuangyingchem.com
Country
CHINA
ProdList
5906
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tel
+86-021-61551413 +8618813727289
Email
contact@trustwe.com
Country
China
ProdList
5743
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Shanghai Ruipu Medical Technology Co., Ltd
Tel
15895968936
Fax
qq 1018762393
Email
1018762393@qq.com
Country
China
ProdList
9999
Advantage
58
Hubei yongkuo Technology Co., Ltd
Tel
027-027-59223108 15972152991
Fax
027-59223108
Email
1248580099@qq.com
Country
China
ProdList
9953
Advantage
58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd
Tel
027-027-59308705 18871579363
Fax
027-59308705
Email
1248680011@qq.com
Country
China
ProdList
9850
Advantage
58
Hubei Shishun Biotechnology Co. Ltd
Tel
027-027-59223025 15107168801
Fax
027-59223025
Email
1718480011@qq.com
Country
China
ProdList
9719
Advantage
58
Hubei Baidu Chemical Co., Ltd
Tel
027-027-59106051 13627137652
Fax
027-59223020
Email
1438180055@qq.com
Country
China
ProdList
8750
Advantage
58
Hubei Guangao Biotechnology Co., Ltd
Tel
027-02702759223056 18162699093
Fax
027-59223056
Email
1208480011@qq.com
Country
China
ProdList
9875
Advantage
58
Hubei Wande Chemical Co., Ltd
Tel
027-027-59210159 15377098680
Fax
027-59210159
Email
1148280011@qq.com
Country
China
ProdList
9835
Advantage
58
More
Less

View Lastest Price from TETRAMETHYL-1,3-CYCLOBUTANEDIONE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
TETRAMETHYL-1,3-CYCLOBUTANEDIONE 933-52-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-07-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
TETRAMETHYL-1,3-CYCLOBUTANEDIONE 933-52-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
TETRAMETHYL-1,3-CYCLOBUTANEDIONE 933-52-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-08

933-52-8, TETRAMETHYL-1,3-CYCLOBUTANEDIONERelated Search:


  • TETRAMETHYL-1,3-CYCLOBUTANEDIONE
  • TETRAMETHYLCYCLOBUTANE-1,3-DIONE
  • TIMTEC-BB SBB008408
  • RARECHEM AQ C4 0041
  • 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIONE
  • DIMETHYL KETENE DIMER
  • 1,1,3,3-Tetramethylcyclobutanedione
  • 2,2,4,4-Tetramethyl cyclobutane-1,3-dione
  • 2,2,4,4-tetramethyl-3-cyclobutanedione
  • 2,2,4,4-Tetramethylcyclobutanedione
  • Tetramethylcyclobuta-1,3-dione
  • Tetramethyl-1,3-cyclobutanedione, GC 99%
  • 1,3-Cyclobutanedione, 2,2,4,4-tetramethyl-
  • Tetramethyl-1,3-cyclobutanedione [Precursor to Dimethyl Ketene]
  • Dimethylkene dimer
  • Tetramethyl-1,3-cyclobutanedione,99%
  • Tetramethyl-1,3-cyclobutanedione 99%
  • NSC 72172
  • NSC 46472
  • [Precursor to DiMethyl Ketene]
  • TetraMethyl-1,3-cyclobutanedione&nbsp
  • TETRAMETHYL-1,3-CYCLOBUTANEDIONE, 99%TETRAMETHYL-1,3-CYCLOBUTANEDIONE, 99%TETRAMETHYL-1,3-CYCLOBUTANEDIONE, 99%TETRAMETHYL-1,3-CYCLOBUTANEDIONE, 99%
  • Tetramethyl-1,3-cyclobutanedione [Precursor to Dimethyl Ketene]&gt
  • Tetramethylcyclobutenedione
  • 933-52-8
  • 933-53-8
  • CH34C4O2
  • Simple 4-Membered Ring Compounds
  • Cyclobutanes & Cyclobutenes
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • C7 to C8
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Organics
  • Cyclobutanes & Cyclobutenes
  • Simple 4-Membered Ring Compounds
  • C7 to C8
  • Carbonyl Compounds
  • Ketones