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CYCLO (ARG-GLY-ASP-D-PHE-LYS)

Product Name
CYCLO (ARG-GLY-ASP-D-PHE-LYS)
CAS No.
161552-03-0
Chemical Name
CYCLO (ARG-GLY-ASP-D-PHE-LYS)
Synonyms
CYCLO;c(RGDfK);CYCLO(-RGDFK);Cyclo(RGDfK) peptide;RGDFK;cyclo(RGD-DPhe-K);Cyclo (-RGDfK) TFA;Cyclo(-RGDfK), >98%;Cyclic RGDFK peptide;ARG-GLY-ASP-D-PHE-LYS
CBNumber
CB1186608
Molecular Formula
C27H41N9O7
Formula Weight
603.67
MOL File
Mol file
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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Property

Melting point:
191℃ (decomposition)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥30.19 mg/mL in DMSO; insoluble in EtOH; ≥59.2 mg/mL in H2O
form 
Powder
pka
4.01±0.10(Predicted)
color 
White to off-white
Sequence
Cyclo(Arg-Gly-Asp-Phe-Lys)
InChIKey
NVHPXYIRNJFKTE-HAGHYFMRSA-N
SMILES
[C@@H]1(NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC1=O)CC1C=CC=CC=1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29514
Product name
Cyclo(RGDfK)
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
29514
Product name
Cyclo(RGDfK)
Packaging
100mg
Price
$1082
Updated
2024/03/01
Cayman Chemical
Product number
29514
Product name
Cyclo(RGDfK)
Packaging
10mg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
29514
Product name
Cyclo(RGDfK)
Packaging
25mg
Price
$481
Updated
2024/03/01
Usbiological
Product number
236998
Product name
Cyclo
Packaging
100mg
Price
$219
Updated
2021/12/16
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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Chemical Properties,Usage,Production

Uses

Cyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.

Biological Activity

in one study where this peptide was labeled with 125i, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. the integrin alpha(iib)beta(3)-specific cyclic hexapeptide contains an arg-gly-asp (rgd) sequence.

target

Integrin

IC 50

αvβ3: 0.94 nM (IC50)

CYCLO (ARG-GLY-ASP-D-PHE-LYS) Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLO (ARG-GLY-ASP-D-PHE-LYS) Suppliers

China 147 Germany 1 Japan 1 United Kingdom 2 United States 19 Global 170
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View Lastest Price from CYCLO (ARG-GLY-ASP-D-PHE-LYS) manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
CYCLO (ARG-GLY-ASP-D-PHE-LYS) 161552-03-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-11
Dideu Industries Group Limited
Product
CYCLO (ARG-GLY-ASP-D-PHE-LYS) 161552-03-0
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-17
GenicBio Limited
Product
Cyclo ( - RGDfK) 161552-03-0
Price
US $1.00/MG
Min. Order
5MG
Purity
>95%
Supply Ability
5mg,10mg,25mg,100mg,1g,10g
Release date
2018-07-29

161552-03-0, CYCLO (ARG-GLY-ASP-D-PHE-LYS)Related Search:


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