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(R)-2-amino-2-(4-hydroxyphenyl)acetamide

Product Name
(R)-2-amino-2-(4-hydroxyphenyl)acetamide
CAS No.
54397-23-8
Chemical Name
(R)-2-amino-2-(4-hydroxyphenyl)acetamide
Synonyms
Amoxicillin Acetamide Impurity;(2R)-2-Amino-2-(4-hydroxyphenyl)ace;(2R)-Amino-2-(4-hydroxyphenyl)acetamide;(R)-2-amino-2-(4-hydroxyphenyl)acetamide;Benzeneacetamide, α-amino-4-hydroxy-, (αR)-
CBNumber
CB11870429
Molecular Formula
C8H10N2O2
Formula Weight
166.18
MOL File
54397-23-8.mol
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(R)-2-amino-2-(4-hydroxyphenyl)acetamide Property

solubility 
Aqueous Acid (Slightly), DMSO (Heated)
form 
Solid
color 
White to Pale Red
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2197
Product name
(2R)-2-Amino-2-(4-hydroxyphenyl)-acetamide
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$689
Updated
2024/03/01
TRC
Product number
H951320
Product name
D-p-Hydroxyphenylglycinamide
Packaging
250mg
Price
$970
Updated
2021/12/16
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(R)-2-amino-2-(4-hydroxyphenyl)acetamide Chemical Properties,Usage,Production

Uses

D-p-Hydroxyphenylglycinamide is an activated side chain precursor and is an intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260), which is a potential impuritiy of the penicillins, ampicillin and amoxicillin, which have not been reported previously. 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone impurity may be formed during the semi-synthetic preparation of these antibiotics or upon their degradation.

(R)-2-amino-2-(4-hydroxyphenyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-amino-2-(4-hydroxyphenyl)acetamide Suppliers