ChemicalBook > CAS DataBase List > Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-

Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-

Product Name: Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-
CAS No.: 898562-94-2
Chemical Name: Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-
Synonyms: MP 10;EOS-61169;PF-2545920(MP-10);MP 10, Mardepodect;PF-2545920 (Mardepodec;Mardepodect, 10 mM in DMSO;PF 2545920; PF2545920;MP10;MP 10;PF-2545920; PF 2545920; PF2545920; MP-10; MP10; MP 10, MARDEPODECT;2-({4-[1-Methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline;2-[(4-(1-Methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl]quinoline
CBNumber: CB11872135
Molecular Formula: C25H20N4O
Formula Weight: 392.45
MOL File: 898562-94-2.mol

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Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]- Property

Melting point:: 180-181 °C
Boiling point:: 568.6±50.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.05 mg/ml; DMSO: 15 mg/ml; Ethanol: 0.5 mg/ml
form: A crystalline solid
pka: 4.32±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0351
Product name: PF-2545920 hydrochloride
Purity: ≥97% (HPLC)
Packaging: 5 mg
Price: $111.15
Updated: 2025/07/31

Sigma-Aldrich

Product number: PZ0351
Product name: PF-2545920 hydrochloride
Purity: ≥97% (HPLC)
Packaging: 25 mg
Price: $477
Updated: 2025/07/31

Cayman Chemical

Product number: 18266
Product name: PF-2545920
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 18266
Product name: PF-2545920
Purity: ≥98%
Packaging: 5mg
Price: $179
Updated: 2024/03/01

Cayman Chemical

Product number: 18266
Product name: PF-2545920
Purity: ≥98%
Packaging: 10mg
Price: $330
Updated: 2024/03/01

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Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]- Chemical Properties,Usage,Production

Biological Activity

PF-2545920 hydrochloride (MP-10) is a potent and selective cyclic nucleotide phosphodiesterase (PDE) 10A competitive inhibitor with a reported IC50 value of 1.26 nM. PDE10A hydrolyzes both cAMP and cGMP, and is highly expressed in medium spiny neurons of the mammalian striatum and in basal ganglia areas where D1 and D2 dopamine receptors are expressed. PF-2545920 has been studied for treatment of schizophrenia and Huntingtonμs disease.

Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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898562-94-2, Quinoline, 2-[[4-[1-methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-Related Search:

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898562-94-2

APIs