ChemicalBook > CAS DataBase List > 2-IMINO-4-METHYLPIPERIDINE ACETATE

2-IMINO-4-METHYLPIPERIDINE ACETATE

Product Name: 2-IMINO-4-METHYLPIPERIDINE ACETATE
CAS No.: 165383-72-2
Chemical Name: 2-IMINO-4-METHYLPIPERIDINE ACETATE
Synonyms: NOS-IN-1;NOS-IN-1u00A0;QNJYWSIQJFUBOR-UHFFFAOYSA-N;NOS-IN-1u00A0, 10 mM in DMSO;2-IMINO-4-METHYLPIPERIDINE ACETATE;(2)-IMINO-4-METHYLPIPERIDINE ACETATE SALT;4-Methyl-3,4,5,6-tetrahydropyridin-2-aMine acetate;3,4,5,6-TETRAHYDRO-4-METHYL-2-PYRIDINAMINE, ACETATE;2-Pyridinamine, 3,4,5,6-tetrahydro-4-methyl-, acetate (1:1);Nitric oxide synthases,NOS IN 1?,oral,NOS,iNOS,NO Synthase,eNOS,nNOS,NOSIN1?,nitrate,Inhibitor,inhibit,nitrite
CBNumber: CB1193822
Molecular Formula: C8H16N2O2
Formula Weight: 172.22
MOL File: 165383-72-2.mol

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2-IMINO-4-METHYLPIPERIDINE ACETATE Property

Melting point:: 181-182°C
storage temp.: Store at -20°C
solubility: DMF: >5 mg/ml; DMSO: >6.5 mg/ml; Ethanol: >23 mg/ml; PBS pH 7.2: >25 mg/ml
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 81015
Product name: 2-Imino-4-methylpiperidine (acetate)
Purity: ≥98%
Packaging: 5mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 81015
Product name: 2-Imino-4-methylpiperidine (acetate)
Purity: ≥98%
Packaging: 10mg
Price: $67
Updated: 2024/03/01

Cayman Chemical

Product number: 81015
Product name: 2-Imino-4-methylpiperidine (acetate)
Purity: ≥98%
Packaging: 25mg
Price: $146
Updated: 2024/03/01

Cayman Chemical

Product number: 81015
Product name: 2-Imino-4-methylpiperidine (acetate)
Purity: ≥98%
Packaging: 50mg
Price: $201
Updated: 2024/03/01

AK Scientific

Product number: 1356AH
Product name: 2-Imino-4-methylpiperidineacetate
Packaging: 25mg
Price: $262
Updated: 2021/12/16

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2-IMINO-4-METHYLPIPERIDINE ACETATE Chemical Properties,Usage,Production

Description

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC₅₀ values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM.

Uses

2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. It exhibits IC50 values of 0.1, 1.1, and 0.2 μM for inhibition of human iNOS, eNOS, and nNOS, respectively, at an arginine concentration of 30 μM.

Uses

A potent inhibitor of human iNOS (hNOS II).

in vivo

Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay^[1].

References

[1] R. KEITH WEBBER. Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms?[J]. Journal of Medicinal Chemistry, 1998, 41 1: 96-101. DOI: 10.1021/jm9705059

2-IMINO-4-METHYLPIPERIDINE ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-IMINO-4-METHYLPIPERIDINE ACETATE Suppliers

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165383-72-2, 2-IMINO-4-METHYLPIPERIDINE ACETATERelated Search:

2-IMINO-4-METHYLPIPERIDINE ACETATE 3-METHYL-BUTYRAMIDINE 2-IMINO-4,6-DIMETHYLPIPERIDINE, ACETATE CHEMBRDG-BB 4012909 BUTYRAMIDINE

4-Methyl-3,4,5,6-tetrahydropyridin-2-aMine acetate

QNJYWSIQJFUBOR-UHFFFAOYSA-N

2-IMINO-4-METHYLPIPERIDINE ACETATE

(2)-IMINO-4-METHYLPIPERIDINE ACETATE SALT

3,4,5,6-TETRAHYDRO-4-METHYL-2-PYRIDINAMINE, ACETATE

NOS-IN-1

Nitric oxide synthases,NOS IN 1?,oral,NOS,iNOS,NO Synthase,eNOS,nNOS,NOSIN1?,nitrate,Inhibitor,inhibit,nitrite

2-Pyridinamine, 3,4,5,6-tetrahydro-4-methyl-, acetate (1:1)

NOS-IN-1u00A0

NOS-IN-1u00A0, 10 mM in DMSO

165383-72-2

C6H12N2C2H4O2

C6H12N2C2H3O2

Nitric Oxide Reagents