1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER
- Product Name
- 1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER
- CAS No.
- 1865-09-4
- Chemical Name
- 1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER
- Synonyms
- 2-(Ethoxycarbonyl)-1H-benzimidazole;Ethyl 1H-benzimidazole-2-carboxylate;ethyl 1H-1,3-benzodiazole-2-carboxylate;Ethyl 1H-1,3-benzimidazole-2-carboxylate;BENZIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER;1H-BENZIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER;1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER;1H-Benzimidazole-2-carboxylicacid,ethylester(9CI)
- CBNumber
- CB1195987
- Molecular Formula
- C10H10N2O2
- Formula Weight
- 190.2
- MOL File
- 1865-09-4.mol
1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER Property
- Melting point:
- 212.7-213.7 °C
- Boiling point:
- 350.0±25.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 10.49±0.10(Predicted)
- color
- Beige
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H260In contact with water releases flammable gases which may ignite spontaneously
H301Toxic if swalloed
H314Causes severe skin burns and eye damage
H330Fatal if inhaled
- Precautionary statements
-
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P231+P232Handle under inert gas. Protect from moisture.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P335+P334Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P363Wash contaminated clothing before reuse.
P370+P378In case of fire: Use … for extinction.
P402+P404Store in a dry place. Store in a closed container.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M164403
- Product name
- Ethyl1H-Benzimidazole-2-carboxylate
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 056339
- Product name
- Ethyl 1H-1,3-benzimidazole-2-carboxylate
- Purity
- >95%
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- OR18118
- Product name
- Ethyl1H-benzimidazole-2-carboxylate
- Purity
- 95%
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
- Product number
- 4H56-1-2A
- Product name
- Ethyl 1H-benzimidazole-2-carboxylate
- Packaging
- 1g
- Price
- $144
- Updated
- 2021/12/16
- Product number
- 056339
- Product name
- Ethyl 1H-1,3-benzimidazole-2-carboxylate
- Purity
- >95%
- Packaging
- 5g
- Price
- $225
- Updated
- 2021/12/16
1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 39, p. 1519, 1974 DOI: 10.1021/jo00924a014
Synthesis
2849-93-6
64-17-5
1865-09-4
1H-benzimidazole-2-carboxylic acid (500 mg, 3.08 mmol) was suspended in anhydrous ethanol (5 mL) and thionyl chloride (1.12 mL, 15.4 mmol) was slowly added dropwise, followed by heating the reaction mixture to reflux and stirring overnight. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to afford the crude product ethyl 1H-benzo[d]imidazole-2-carboxylate (644 mg, 99% yield).
References
[1] Patent: WO2006/91506, 2006, A2. Location in patent: Page/Page column 42
[2] Patent: WO2006/49681, 2006, A2. Location in patent: Page/Page column 40
[3] Patent: WO2006/121588, 2006, A2. Location in patent: Page/Page column 46
[4] Patent: WO2006/121860, 2006, A2. Location in patent: Page/Page column 46
[5] Patent: WO2006/121904, 2006, A1. Location in patent: Page/Page column 46
1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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