O-PHENYLHYDROXYLAMINE HYDROCHLORIDE
- Product Name
- O-PHENYLHYDROXYLAMINE HYDROCHLORIDE
- CAS No.
- 6092-80-4
- Chemical Name
- O-PHENYLHYDROXYLAMINE HYDROCHLORIDE
- Synonyms
- O-phenylhydroxylamine;o-PhenylhydroxylamineHCl;PHENOXYAMINE HYDROCHLORIDE;O-Phenylhydroxyamine hydrochloride;O-PHENYLHYDROXYLAMINE HYDROCHLORIDE;(Aminooxy)benzene hydrochloride (1:1);HydroxylaMine, O-phenyl-, hydrochloride;O-Phenylhydroxylamine hydrochloride, 97%,;O-Phenylhydroxylamine hydrochloride;Hydroxylamine, O-phenyl-, hydrochloride (1:1)
- CBNumber
- CB1208829
- Molecular Formula
- C6H8ClNO
- Formula Weight
- 145.59
- MOL File
- 6092-80-4.mol
O-PHENYLHYDROXYLAMINE HYDROCHLORIDE Property
- Melting point:
- ~132 °C (dec.)
- storage temp.
- 2-8°C
- form
- Powder
- color
- White to yellow
- BRN
- 4326059
- InChI
- InChI=1S/C6H7NO.ClH/c7-8-6-4-2-1-3-5-6;/h1-5H,7H2;1H
- InChIKey
- DBTXKJJSFWZJNS-UHFFFAOYSA-N
- SMILES
- C1(ON)C=CC=CC=1.Cl
- CAS DataBase Reference
- 6092-80-4
Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-25
- Safety Statements
- 16-22-24/25-45
- RIDADR
- UN2811 6.1/PG 3
- WGK Germany
- 3
- F
- 4.6-10-21
- HS Code
- 2928009090
N-Bromosuccinimide Price
- Product number
- 78725
- Product name
- O-Phenylhydroxylamine hydrochloride
- Purity
- 97%
- Packaging
- 1g
- Price
- $196
- Updated
- 2025/07/31
- Product number
- P336558
- Product name
- O-Phenylhydroxylamine hydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P336558
- Product name
- O-Phenylhydroxylamine hydrochloride
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- P336558
- Product name
- O-Phenylhydroxylamine hydrochloride
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 9106AB
- Product name
- O-Phenylhydroxylamine hydrochloride
- Packaging
- 1g
- Price
- $162
- Updated
- 2021/12/16
O-PHENYLHYDROXYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Synthesis
4846-21-3
6092-80-4
General procedure for the synthesis of O-phenylhydroxylamine hydrochloride from compound (CAS: 4846-21-3): a representative method for the preparation of the corresponding O-arylhydroxylamine by hydrazinolysis of N-aryloxyphthalimide (Method 1A): synthesis of compound 1; hydrazine monohydrate (0.401 mL, 8.2 mmol) was slowly added to N-phenoxyphthalimide 9 ( 652 mg, 2.73 mmol) dissolved in a 10% MeOH solution of CHCl3 (25 mL) and the reaction was stirred at room temperature. Upon completion of the reaction (monitored by TLC, 12 h), a white precipitate (phthalazine) appeared in the colorless reaction solution. The reaction mixture was filtered through a silica gel plug and washed with a hexane solution of 30% EtOAc. Removal of EtOAc/hexane gave a light yellow oil, which was distilled by Kugelrohr to give pure phenoxyamine 1 as a clear, colorless oil (238 mg, 80% yield) from K2CO3 (<10 mg); the characterization data are given below. Alternatively, after removal of EtOAc/hexane, the yellow oily substance was dissolved in Et2O and cooled to 0 °C. After being kept at 0 °C for 10 min, a solution of 4N HCl in dioxane was added dropwise until the pH reached 3. The resulting white solid was filtered and washed with Et2O (2 × 10 mL) to give the pure HCl salt (306 mg, 77% yield) of 1. O-Phenylhydroxylamine hydrochloride (1) was prepared as described above as a representative procedure (Method 1A). 1H-NMR (400 MHz , CD3OD) δ 6.84-6.89 (m, 1H), 7.03-7.09 (m, 2H), 7.19-7.25 (m, 2H); 13C-NMR (100 MHz, CD3OD) δ 114.1, 121.6, 130.3, 163.1; LC-MS m/z 110 [MH]+, theoretical value for C6H8NO 110.
References
[1] Patent: US2006/178527, 2006, A1. Location in patent: Page/Page column 8; sheet 6
[2] Synlett, 2009, # 18, p. 3003 - 3006
O-PHENYLHYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
O-PHENYLHYDROXYLAMINE HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- fo@acros.com
- Country
- Belgium
- ProdList
- 3824
- Advantage
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View Lastest Price from O-PHENYLHYDROXYLAMINE HYDROCHLORIDE manufacturers
- Product
- O-PHENYLHYDROXYLAMINE HYDROCHLORIDE 6092-80-4
- Price
- US $1.00-4.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000KG
- Release date
- 2025-09-04
- Product
- O-PHENYLHYDROXYLAMINE HYDROCHLORIDE 6092-80-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-31
- Product
- O-Phenylhydroxylamine hydrochloride 6092-80-4
- Price
- US $1.35-568.00/Kg
- Min. Order
- 1Kg
- Purity
- 99%
- Supply Ability
- 100000
- Release date
- 2023-03-20