ChemicalBook > CAS DataBase List > Glutathione Ethyl Ester

Glutathione Ethyl Ester

Product Name
Glutathione Ethyl Ester
CAS No.
92614-59-0
Chemical Name
Glutathione Ethyl Ester
Synonyms
GSH monoethylester;L-αGlu-L-Cys-Gly-OEt;H-GLU(CYS-GLY-OET)-OH;Glutathione Ethyl Ester;L-αGlu-L-Cys-Gly-Ethyl OH;γ-Glu-Cys-Gly-OEt, GSH-MEE;GLUTATHIONE MON ETHYL ESTER;Glutatione Reduced Ethyl Ester;GLUTATHIONE REDUCED FORM, ETHYL ESTE;Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester
CBNumber
CB12130580
Molecular Formula
C12H21N3O6S
Formula Weight
335.38
MOL File
92614-59-0.mol
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Glutathione Ethyl Ester Property

Boiling point:
644.3±55.0 °C(Predicted)
Density 
1.314±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
form 
A crystalline solid
pka
2.21±0.10(Predicted)
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G1404
Product name
Glutathione reduced ethyl ester
Purity
≥90% (TLC)
Packaging
25mg
Price
$80.1
Updated
2024/03/01
Sigma-Aldrich
Product number
G1404
Product name
Glutathione reduced ethyl ester
Purity
≥90% (TLC)
Packaging
100mg
Price
$235
Updated
2024/03/01
Cayman Chemical
Product number
14953
Product name
Glutathione ethyl ester
Purity
≥95%
Packaging
50mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
14953
Product name
Glutathione ethyl ester
Purity
≥95%
Packaging
100mg
Price
$95
Updated
2024/03/01
Cayman Chemical
Product number
14953
Product name
Glutathione ethyl ester
Purity
≥95%
Packaging
500mg
Price
$350
Updated
2024/03/01
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Glutathione Ethyl Ester Chemical Properties,Usage,Production

Description

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Uses

Glutathione (GSH) serves as a nucleophilic co-substrate to glutathione transferase in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides. GSH ethyl ester is a cell permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals.

Uses

Glutathione reduced ethyl ester has been used:

  • to increase intracellular glutathione levels in mouse fibroblast L929 cells
  • as a medium supplement in Spodoptera frugiperda (Sf)9 cells
  • to evaluate its effect on lipid peroxidation after spinal cord injury

Biochem/physiol Actions

Glutathione reduced ethyl ester (GSH-MEE) is a membrane/lipid permeable derivative of GSH that may be used to partially supplement the GSH supply within cells subjected to cysteine and/or GSH depletion. GSH-MEE is hydrolysed by intracellular esterases to release GSH, thereby increases the concentrations of intracellular GSH. It prevents the toxic effects of acetaminophen in animal cells. It protects human lymphoid cells and skin fibroblasts against the damage caused due to radiation.

Glutathione Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Glutathione Ethyl Ester Suppliers

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View Lastest Price from Glutathione Ethyl Ester manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
Glutatione Reduced Ethyl Ester 92614-59-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2023-11-03

92614-59-0, Glutathione Ethyl EsterRelated Search:

CYS-GLY

  • H-GLU(CYS-GLY-OET)-OH
  • Glutathione Ethyl Ester
  • γ-Glu-Cys-Gly-OEt, GSH-MEE
  • GSH monoethylester
  • L-αGlu-L-Cys-Gly-Ethyl OH
  • L-αGlu-L-Cys-Gly-OEt
  • Glycine, L-gamma-glutamyl-L-cysteinyl-, 3-ethyl ester
  • GLUTATHIONE REDUCED FORM, ETHYL ESTE
  • L-gamma-Glutamyl-L-cysteinylglycine 3-ethyl ester
  • Glycine, L-γ-glutamyl-L-cysteinyl-, 3-ethyl ester
  • Glutathione-monoethyl ester (reduced) H-Glu(Cys-Gly-OEt)-OH
  • GLUTATHIONE MON ETHYL ESTER
  • Glutatione Reduced Ethyl Ester
  • 92614-59-0