ChemicalBook > CAS DataBase List > 3,3-Bis(methylthio)-2-cyanopropenamide

3,3-Bis(methylthio)-2-cyanopropenamide

Product Name
3,3-Bis(methylthio)-2-cyanopropenamide
CAS No.
17823-69-7
Chemical Name
3,3-Bis(methylthio)-2-cyanopropenamide
Synonyms
DM8;3-Bis(methylthio)-2-cyanopropenamide;2-Cyano-3,3-bis(methylthio)acrylamide;3,3-Bis(methylthio)-2-cyanopropenamide;2-cyano-3,3-bis(methylthio)-2-Propenamide;2-Cyano-3,3-bis(methylsulphanyl)acrylamide;2-Propenamide, 2-cyano-3,3-bis(methylthio)-;2-cyano-3,3-bis(methylsulfanyl)prop-2-enamide
CBNumber
CB12157525
Molecular Formula
C6H8N2OS2
Formula Weight
188.27
MOL File
17823-69-7.mol
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3,3-Bis(methylthio)-2-cyanopropenamide Property

Melting point:
101-102 °C
Boiling point:
349.7±42.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
11.74±0.50(Predicted)
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Safety

HS Code 
2930909899
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific
Product number
097130
Product name
2-Cyano-3,3-bis(methylthio)acrylamide
Purity
95+%
Packaging
250mg
Price
$165
Updated
2021/12/16
AK Scientific
Product number
9347AA
Product name
2-Cyano-3,3-bis(methylthio)acrylamide
Packaging
1g
Price
$298
Updated
2021/12/16
Matrix Scientific
Product number
097130
Product name
2-Cyano-3,3-bis(methylthio)acrylamide
Purity
95+%
Packaging
1g
Price
$455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0388116
Product name
2-CYANO-3,3-BIS(METHYLTHIO)ACRYLAMIDE
Purity
95.00%
Packaging
5MG
Price
$496.21
Updated
2021/12/16
BroadPharm
Product number
BP-20705
Product name
2-cyano-3,3-bis(methylthio)acrylamide
Purity
98%
Packaging
5G
Price
$750
Updated
2021/12/16
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3,3-Bis(methylthio)-2-cyanopropenamide Chemical Properties,Usage,Production

Synthesis

75-15-0

77-78-1

107-91-5

17823-69-7

Preparation of 2-cyano-3,3-bis(methylthio)acrylamide: A mixture of cyanoacetamide (10 g, 118.9 mmol) and potassium hydroxide (6.661 g, 118.9 mmol) in acetonitrile (100 mL) was stirred for 1 hour at room temperature. Subsequently, carbon disulfide (9.054 g, 118.9 mmol) was slowly added at the same temperature and stirring was continued for 3 hours. Next, dimethyl sulfate (19.5 g, 154.6 mmol) was added and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the volatiles were removed under vacuum and the residue was redissolved in ethyl acetate, washed sequentially with water and brine, dried over anhydrous magnesium sulfate, and subsequently concentrated under vacuum. The resulting solid was ground with a solvent mixture of ethyl acetate/hexane, filtered and dried to afford the target compound 2-cyano-3,3-bis(methylthio)acrylamide (9.4 g, 42% yield, 99.0% purity) as a yellow solid.

References

[1] Patent: US2016/176857, 2016, A1. Location in patent: Paragraph 0275
[2] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 24, p. 5453 - 5458
[3] Journal of Agricultural and Food Chemistry, 2008, vol. 56, # 13, p. 5242 - 5246
[4] Journal of Heterocyclic Chemistry, 2011, vol. 48, # 4, p. 901 - 906

3,3-Bis(methylthio)-2-cyanopropenamide Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3-Bis(methylthio)-2-cyanopropenamide Suppliers

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17823-69-7, 3,3-Bis(methylthio)-2-cyanopropenamideRelated Search:


  • 2-Cyano-3,3-bis(methylthio)acrylamide
  • 3,3-Bis(methylthio)-2-cyanopropenamide
  • 2-cyano-3,3-bis(methylsulfanyl)prop-2-enamide
  • 3-Bis(methylthio)-2-cyanopropenamide
  • 2-cyano-3,3-bis(methylthio)-2-Propenamide
  • 2-Propenamide, 2-cyano-3,3-bis(methylthio)-
  • DM8
  • 2-Cyano-3,3-bis(methylsulphanyl)acrylamide
  • 17823-69-7