ChemicalBook > CAS DataBase List > Di-tert-butyl N,N-diethylphosphoramidite

Di-tert-butyl N,N-diethylphosphoramidite

Product Name
Di-tert-butyl N,N-diethylphosphoramidite
CAS No.
117924-33-1
Chemical Name
Di-tert-butyl N,N-diethylphosphoramidite
Synonyms
DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE;N-ditert-butoxyphosphanyl-N-ethyl-ethanamine;Diethyl diethylphosphoramidite;DI-T-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;Di-tert-butyl N,N-diethylphosphoraMidit;DI-TERT-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL-N,N-DIETHYLPHOSPHOROAMIDITE;Di-t-butyl N,N-Diethylphosphoramidite (~90%);DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE, TE CH., 93%;Bis(1,1-dimethylethyl) N,N-diethylphosphoramidite
CBNumber
CB1216525
Molecular Formula
C12H28NO2P
Formula Weight
249.33
MOL File
117924-33-1.mol
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Di-tert-butyl N,N-diethylphosphoramidite Property

Boiling point:
39-41 °C/0.3 mmHg (lit.)
Density 
0.896 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.434(lit.)
Flash point:
173 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Oil
pka
4.41±0.70(Predicted)
color 
Clear Colourless
Water Solubility 
Hydrolyzes in water. Soluble in chloroform and methanol.
Sensitive 
Moisture Sensitive
BRN 
4175262
Stability:
Moisture Sensitive
InChI
InChI=1S/C12H28NO2P/c1-9-13(10-2)16(14-11(3,4)5)15-12(6,7)8/h9-10H2,1-8H3
InChIKey
KUKSUQKELVOKBH-UHFFFAOYSA-N
SMILES
P(N(CC)CC)(OC(C)(C)C)OC(C)(C)C
CAS DataBase Reference
117924-33-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
4.4-10-21
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
365963
Product name
Di-tert-butyl N,N-diethylphosphoramidite
Purity
technical grade, 93%
Packaging
1g
Price
$98.8
Updated
2025/07/31
Sigma-Aldrich
Product number
365963
Product name
Di-tert-butyl N,N-diethylphosphoramidite
Purity
technical grade, 93%
Packaging
5g
Price
$260
Updated
2025/07/31
TRC
Product number
D429300
Product name
Di-t-butylN,N-Diethylphosphoramidite(~90%)
Packaging
5g
Price
$185
Updated
2021/12/16
TRC
Product number
D429300
Product name
Di-t-butylN,N-Diethylphosphoramidite(~90%)
Packaging
10g
Price
$360
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ING0002795
Product name
DI-TERT-BUTYL N,N-DIETHYLPHOSPHORAMIDITE
Purity
95.00%
Packaging
5G
Price
$900
Updated
2021/12/16
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Di-tert-butyl N,N-diethylphosphoramidite Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Liquid

Uses

A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

Uses

Di-tert-butyl N,N-diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters.

Di-tert-butyl N,N-diethylphosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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Di-tert-butyl N,N-diethylphosphoramidite Suppliers

Xinxiang Runyu Material Co., Ltd.
Tel
166-166-37336996 15690792173
Fax
0373-7759608
Email
chenxi.song@runvmat.com
Country
China
ProdList
285
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
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China
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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Beijing Ouhe Technology Co., Ltd
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010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
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Beijing VSciChem Technology Co., Ltd.
Tel
13811761079
Email
vscichem@163.com
Country
China
ProdList
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
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Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
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59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
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50
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View Lastest Price from Di-tert-butyl N,N-diethylphosphoramidite manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Di-tert-butyl N,N-diethylphosphoramidite 117924-33-1
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-15
Zhuozhou Wenxi import and Export Co., Ltd
Product
Di-tert-butyl N,N-diethylphosphoramidite 117924-33-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
Di-tert-butyl N,N-diethylphosphoramidite 117924-33-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons/month
Release date
2020-01-08

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