ChemicalBook > CAS DataBase List > (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER

(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER

Product Name: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
CAS No.: 88496-70-2
Chemical Name: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
Synonyms: (R)-4-CHLORO-3-HYDROXYBUTYRATE;(R)-Methyl-4-cloro-3-hydroxybut;(R)-Methyl-4-cloro-3-hydroxybutyrate;(R)-METHYL 4-CHLORO-3-HYDROXYBUTYRATE;METHYL (R)-4-CHLORO-3-HYDROXYBUTYRATE;(R)-Methyl 4-chloro-3-hydroxybutanoate;Methyl (R)-4-Chloro-3-hydroxybutanoate;Methyl(R)-4-Chloro-3-hydroxybutyrate>(R)-4-Chloro-3-hydroxybutyric acid methyl;Methyl (R)-4-Chloro-3-hydroxybutyrate
CBNumber: CB1220490
Molecular Formula: C5H9ClO3
Formula Weight: 152.58
MOL File: 88496-70-2.mol

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(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER Property

Boiling point:: 248.6±20.0 °C(Predicted)
Density: 1.232±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 12.73±0.20(Predicted)
CAS DataBase Reference: 88496-70-2(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36
HS Code: 2918199890

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C381785
Product name: (R)-4-Chloro-3-hydroxybutyricAcidMethylEster
Packaging: 50mg
Price: $60
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0009354
Product name: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
Purity: 95.00%
Packaging: 1G
Price: $619.7
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0009354
Product name: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
Purity: 95.00%
Packaging: 2.5G
Price: $796.77
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0009354
Product name: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER
Purity: 95.00%
Packaging: 5G
Price: $912.29
Updated: 2021/12/16

Matrix Scientific

Product number: 095812
Product name: (R)-Methyl 4-chloro-3-hydroxybutanoate
Purity: 95+%
Packaging: 5g
Price: $168
Updated: 2021/12/16

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(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Synthesis

114819-45-3

88496-70-2

The general procedure for the synthesis of (R)-4-chloro-3-hydroxybutanoic acid methyl ester from the compound (CAS:114819-45-3) is as follows: to a solution of (R)-3-hydroxybutanoic acid methyl ester (125.1 g, 0.93 mol) in methylene chloride (1.8 L) was added triphenylphosphine (244.5 g, 0.93 mol), and under cooling in an ice-water bath, the N- chlorosuccinimide (124.2 g, 0.93 mol) was added slowly under cooling in an ice water bath. The reaction mixture was stirred at 5 °C for 20 min, followed by continued stirring at room temperature for 18 h. The reaction was carried out at room temperature. Upon completion of the reaction, the solvent was removed by evaporation and the residue was purified by column chromatography (petroleum ether/ethyl acetate, 20:1 to 5:1, gradient elution) to afford the target product (R)-methyl (R)-4-chloro-3-hydroxybutanoate (33 g, three-step overall yield 26%). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 4.18-4.25 (m, 1H), 3.68 (s, 3H), 3.55-3.60 (m, 2H), 3.32-3.33 (d, J = 4.2 Hz, 1H), 2.52-2.68 (m, 2H).

References

[1] Patent: WO2007/21982, 2007, A2. Location in patent: Page/Page column 67-68

(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER Suppliers

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View Lastest Price from (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (R)-4-Chloro-3-hydroxybutyric acid methyl ester 88496-70-2
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-24

Zhuozhou Wenxi import and Export Co., Ltd

Product: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER 88496-70-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER 88496-70-2
Price: US $0.01/KG
Min. Order: 500g
Purity: 98%; 99%
Supply Ability: 500g；1kg； 10kg; 25kg
Release date: 2020-01-08

88496-70-2, (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTERRelated Search:

3-Hydroxybutyric acid Methyl 4-chloro-3-hydroxybutyrate (R)-4-CHLORO-1,3-BUTANEDIOL Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate Methyl 4-chlorobutyrate 4-Chloro-3-hydroxy-butyricacidmethylester (R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER

(R)-Methyl-4-cloro-3-hydroxybutyrate

METHYL (R)-4-CHLORO-3-HYDROXYBUTYRATE

(R)-METHYL 4-CHLORO-3-HYDROXYBUTYRATE

(R)-(+)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER

(R)-4-CHLORO-3-HYDROXYBUTYRIC ACID METHYL ESTER

Methyl (<i>R</i>)-4-Chloro-3-hydroxybutyrate

(R/S)4-Chloro-3-hydroxybutyric Acid Methyl ester

(R)-Methyl 4-chloro-3-hydroxybutanoate

(R)-4-Chloro-3-hydroxybutyric acid methyl

(R)-4-CHLORO-3-HYDROXYBUTYRATE

(R)-Methyl-4-cloro-3-hydroxybut

Methyl(R)-4-Chloro-3-hydroxybutyrate&gt

Butanoic acid, 4-chloro-3-hydroxy-, methyl ester, (3R)-

Methyl (R)-4-Chloro-3-hydroxybutanoate

88496-70-2

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