ChemicalBook > CAS DataBase List > [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one

Product Name
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
CAS No.
546-78-1
Chemical Name
[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
Synonyms
Thujenone;Thujen-2-one;(-)-Umbellulone;(1R,5S)-(-)-3-Thujen-2-one;(-)-Umbellulone >=98% (HPLC);(1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one;[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
CBNumber
CB12235115
Formula Weight
0
MOL File
546-78-1.mol
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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Property

storage temp. 
-20°C
solubility 
DMSO : 250 mg/mL (1664.23 mM; Need ultrasonic)
form 
Oil
color 
colorless to light brown
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Safety

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
36/37
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0782
Product name
(-)-Umbellulone
Purity
≥98% (HPLC)
Packaging
5mg
Price
$82.9
Updated
2024/03/01
Adipogen Life Sciences
Product number
AG-CN2-0085-M010
Product name
Umbellulone
Purity
≥98%(HPLC)
Packaging
10mg
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0045882
Product name
(-)-UMBELLULONE
Purity
95.00%
Packaging
5MG
Price
$517.66
Updated
2021/12/16
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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Chemical Properties,Usage,Production

Definition

ChEBI: Umbellulone is a ketone.

Biochem/physiol Actions

(-)-Umbellulone, isolated from the"headache tree" Umbellularia californica Nutt, is a selective activator of Transient Receptor Potential Anykrin 1 (TRPA1) channels. (-)-Umbellulone activates TRPA1 channels on nociceptive trigeminal afferents, resulting in release of CGRP and CGRP-mediated neurogenic vasodilatation, causing a painful cold sensation and headache/migraine.

[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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[1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one Suppliers

China 9 United States 3 Global 12
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
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80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
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Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
4870
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58
Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel
02961856358 15829046862
Email
1035@dideu.com
Country
China
ProdList
10011
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58
RD International Technology Co., Limited
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9272
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19711
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58

546-78-1, [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-oneRelated Search:


  • [1R,5S,(-)]-4-Methyl-1-isopropylbicyclo[3.1.0]hexa-3-ene-2-one
  • (1R, 5S)-4-Methyl-1-propan-2-ylbicyclo(3.1.0)hex-3-en-2-one
  • (1R,5S)-(-)-3-Thujen-2-one
  • Thujen-2-one
  • Thujenone
  • (-)-Umbellulone >=98% (HPLC)
  • (-)-Umbellulone
  • 546-78-1