ChemicalBook > CAS DataBase List > GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
- Product Name
- GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
- CAS No.
- 479065-85-5
- Chemical Name
- GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL
- Synonyms
- ORN8, UROTENSIN II, HUMAN;GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL;L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (5→10)-disulfide (9CI)
- CBNumber
- CB1224201
- Molecular Formula
- C63H83N13O18S2
- Formula Weight
- 1374.54
- MOL File
- Mol file
More
Less
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL Property
- storage temp.
- Desiccate at -20°C
- solubility
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- form
- solid
- color
- White lyophilised
More
Less
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL Chemical Properties,Usage,Production
Description
Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from FRAT1, the mammalian version of GSK-3-binding protein. Binds to GSK-3, inhibiting its interaction with axin, and also blocks GSK-3-catalyzed phosphorylation of axin and β-catenin. Does not affect GSK-3-mediated phosphorylation of glycogen synthase or eIF2B.
GLU-THR-PRO-ASP-CYS-PHE-TRP-ORN-TYR-CYS-VAL Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less