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3-Amino-2-hydroxybenzyl alcohol

Product Name
3-Amino-2-hydroxybenzyl alcohol
CAS No.
52820-13-0
Chemical Name
3-Amino-2-hydroxybenzyl alcohol
Synonyms
2-Amino-4-(hydroxymethyl)phenol;3-Amino-2-hydroxybenzyl alcohol;1,3-Propanediol,1-(8-piperidinyl)-;Benzenemethanol, 3-amino-4-hydroxy-
CBNumber
CB12244878
Molecular Formula
C7H9NO2
Formula Weight
139.15
MOL File
52820-13-0.mol
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3-Amino-2-hydroxybenzyl alcohol Property

Boiling point:
337.4±32.0 °C(Predicted)
Density 
1.338±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light, stored under nitrogen
pka
9.54±0.18(Predicted)
Appearance
Light brown to brown Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
2060CT
Product name
2-Amino-4-(hydroxymethyl)phenol
Packaging
100mg
Price
$135
Updated
2021/12/16
AK Scientific
Product number
2060CT
Product name
2-Amino-4-(hydroxymethyl)phenol
Packaging
250mg
Price
$180
Updated
2021/12/16
Crysdot
Product number
CD12064857
Product name
2-Amino-4-(hydroxymethyl)phenol
Purity
97%
Packaging
100mg
Price
$119
Updated
2021/12/16
Crysdot
Product number
CD12064857
Product name
2-Amino-4-(hydroxymethyl)phenol
Purity
97%
Packaging
250mg
Price
$190
Updated
2021/12/16
Alichem
Product number
52820130
Product name
2-Amino-4-(hydroxymethyl)phenol
Packaging
250mg
Price
$211.2
Updated
2021/12/16
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3-Amino-2-hydroxybenzyl alcohol Chemical Properties,Usage,Production

Synthesis

3011-34-5

52820-13-0

95-84-1

General procedure for the synthesis of 2-amino-4-(hydroxymethyl)phenol and o-amino-p-cresol from 4-hydroxy-3-nitrobenzaldehyde: A mixture of 0.30 g (1.8 mmol) of 4-hydroxy-3-nitrobenzaldehyde with 0.15 g of 10% Pd/C catalyst in 30 mL of ethanol was placed in a hydrogenation reactor and reacted with oscillation for 4 hours under hydrogen atmosphere at 30 psi. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and carefully washed with ethyl acetate. After concentrating the filtrate, it was separated by silica gel column chromatography using a solvent mixture of dichloromethane and methanol (9:1) as eluent to give 91 mg (41% yield) of 2-amino-4-(hydroxymethyl)phenol and 0.10 g (41% yield) of o-amino-p-toluol. Characterization data for compound 2-amino-4-(hydroxymethyl)phenol: IR (pure) ν 3370 (sharp, medium intensity), 3301 (sharp, medium intensity), 2921, 1601, 1519, 1458, 1388, 1286, 878, 800 cm^-1 ; ^1H NMR δ 6.62 (d, J = 7.6 Hz, 1H), 6.58 (d, J = 1.6 Hz, 1H), 6.48 (dd, J = 7.6, 1.6 Hz, 1H), 2.21 (s, 3H); ^13C NMR δ 141.9, 134.4, 131.2, 120.0, 118.1, 115.4, 20.9. Characterization data for the compound o-amino-p-cresol: IR (pure) ν 3387 (sharp, medium intensity), 3313 (sharp, medium intensity), 3047 (broad), 2802, 1605, 1515, 1454, 1364, 1286, 1221, 1155, 1008, 816 cm^-1; ^1H NMR (D2O) δ 6.88 (d , J = 1.2 Hz, 1H), 6.85 (d, J = 8 Hz, 1H), 6.77 (dd, J = 8, 1.2 Hz, 1H), 4.49 (s, 2H); ^13C NMR (DMSO-d6) δ 142.9, 136.1, 133.5, 114.9, 113.8, 113.4, 63.3.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 5, p. 1679 - 1689

3-Amino-2-hydroxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Amino-2-hydroxybenzyl alcohol Suppliers

China 32 India 1 United States 2 Global 35
Yancheng KangdiSen Pharmaceutical Co., Ltd.
Tel
13812573443
Fax
-
Email
tongbenwan22@163.com
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China
ProdList
1980
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55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
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China
ProdList
131957
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Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
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China
ProdList
15814
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58
Jurong Coupling Biotechnology Co., Ltd.
Tel
19231718652
Email
278191416@qq.com
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China
ProdList
482
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Shanghai HongMin Pharmaceutical Co., Ltd.
Tel
13651987816
Fax
-
Email
hongminpharm@163.com
Country
China
ProdList
2326
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58
Shanghai Sealing Biotechnology Co. Ltd..
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15721176654
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1815535157@qq.com
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China
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881
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Shanghai Maruhua Science and Technology Co. Ltd.
Tel
021-57171708 18721745940
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QQ1139783351
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sales@api-chem.com
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China
ProdList
1968
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Suzhou Rovathin Foreign Trade Co.,Ltd
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0512-65816829 18662214788
Fax
0512-65816829
Email
info@rovathin.com.cn
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China
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9987
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Shanghai yuanzuo medical technology co., LTD
Tel
021-31775309; 15221510662
Email
yi_shiyan@yuanzuopharm.com
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China
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139
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Wuxi Donghe Pharmaceutical Technology Co., Ltd.
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63313187 15358055255
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QQ：63313187
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63313187@qq.com
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China
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1984
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52820-13-0, 3-Amino-2-hydroxybenzyl alcoholRelated Search:


  • 3-Amino-2-hydroxybenzyl alcohol
  • Benzenemethanol, 3-amino-4-hydroxy-
  • 2-Amino-4-(hydroxymethyl)phenol
  • 1,3-Propanediol,1-(8-piperidinyl)-
  • 52820-13-0