2-Methyl-2-hydroxypropionamide
- Product Name
- 2-Methyl-2-hydroxypropionamide
- CAS No.
- 13027-88-8
- Chemical Name
- 2-Methyl-2-hydroxypropionamide
- Synonyms
- Methyl-2-lactamide;2-Methyl-2-hydroxypr;α-Hydroxyisobutyramide;2-Hydroxyisobutylamide;2-HYDROXYISOBUTYRAMIDE;2-Hydroxyisobutyramide>2-Methyl-2-hydroxypropiomide;2-Hydroxyisobutyric acid amid;2-HYDROXY-2-METHYLPROPANAMIDE;2-hydroxy-2-methyl-propanamid
- CBNumber
- CB1225091
- Molecular Formula
- C4H9NO2
- Formula Weight
- 103.12
- MOL File
- 13027-88-8.mol
2-Methyl-2-hydroxypropionamide Property
- Melting point:
- 93 °C
- Boiling point:
- 260 °C
- Density
- 1.109±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly), Water (Sparingly)
- form
- Solid
- pka
- 13.41±0.29(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 13027-88-8(CAS DataBase Reference)
- EPA Substance Registry System
- Propanamide, 2-hydroxy-2-methyl- (13027-88-8)
Safety
- HS Code
- 2924.19.8000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H1181
- Product name
- 2-Hydroxyisobutyramide
- Purity
- >98.0%(N)
- Packaging
- 25g
- Price
- $109
- Updated
- 2025/07/31
- Product number
- H513440
- Product name
- 2-Hydroxy-2-methylpropanamide
- Packaging
- 5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- G836
- Product name
- 2-Hydroxyisobutyramide
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- G836
- Product name
- 2-Hydroxyisobutyramide
- Packaging
- 5g
- Price
- $54
- Updated
- 2021/12/16
- Product number
- G836
- Product name
- 2-Hydroxyisobutyramide
- Packaging
- 25g
- Price
- $147
- Updated
- 2021/12/16
2-Methyl-2-hydroxypropionamide Chemical Properties,Usage,Production
Uses
2-Hydroxy-2-methylpropanamide is an anti-crushing agent; used in preparation method for polymerization of Propylene and device.
Synthesis
75-86-5
13027-88-8
The general procedure for the synthesis of 2-hydroxyisobutyramide from acetone cyanohydrin (ACH) is as follows: Hydration reaction Example 1 (0151) was carried out using the reaction apparatus shown in Figure 1. Reactors 1a, 1b and 1c were made of glass with an inner diameter of about 18 mm, equipped with jackets (as first, second and third reactors, respectively). The first reaction region 2a was filled with 16 g of pre-prepared catalyst, the second reaction region 2b was similarly filled with 16 g of catalyst and the third reaction region 2c was filled with 8 g of catalyst. The first reaction feedstock liquid is supplied at a rate of 14.8 g/hr through supply line 3a and is composed of 55.5 wt% pure water, 9.5 wt% acetone, and 35 wt% ACH. the second reaction feedstock liquid is supplied at a rate of 2.47 g/hr through supply line 3b and is composed of 17 wt% pure water, 13 wt% acetone, and 70 wt% ACH. the first reaction feedstock liquid of the ACH accounted for 75 wt% of the total ACH supply. The first oxidizer supply line 4a is supplied with oxygenated gas (9% oxygen and 91% nitrogen, v/v) at a rate of 26.7 ml/hr. This gas passes through the first reaction area 2a and enters the reaction liquid pool 12a via the effluent line 11a, and is subsequently completely discharged from the system via the withdrawal line 5a. A second oxidizer supply line 4b supplies, at the same rate, an oxygenated gas of the same composition, which passes through the second reaction region 2b, enters the reaction liquid pool 12b via the effluent line 11b, and is subsequently directed through the liquid supply line 10c to the third reactor 1c, which ultimately exits the system through the third reaction region 2c and the effluent line 11c. The outlet reaction liquid from the first reaction region is collected in the reaction liquid pool 12a and partially circulated to the inlet of the first reaction region through the circulation line 6a at a rate of 120 g/hr, with a circulation ratio of 8.1. The reaction liquid pool 12a is equipped with a level sensor, and the effluent in excess of 120 g/hr is transferred to the second reaction region through the transfer line 13a, with a constant level controlled by the sensor and the transfer pump 8t. The transfer rate is 14.8 g/hr. The outlet reaction liquid of the second reaction zone is collected in the reaction liquid pool 12b and partially circulated to the inlet of the second reaction zone through the circulation line 6b at a rate of 26.5 g/hr, with a circulation ratio of 1.5. The effluent in excess of 26.5 g/hr is transferred to the third reactor 1c through the liquid transfer line 13b. Note that the oxygenated gas supplied by the second oxidant supply line is transported to the third reactor.
References
[1] Russian Journal of Physical Chemistry, 1984, p. 471 - 472
[2] Zhurnal Fizicheskoi Khimii, 1984, vol. 58, # 3, p. 772 - 775
[3] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1991, # 3, p. 417 - 422
[4] Patent: US2229897, 1940,
[5] Bulletin des Societes Chimiques Belges, 1930, vol. 39, p. 563
2-Methyl-2-hydroxypropionamide Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-Methyl-2-hydroxypropionamide manufacturers
- Product
- 2-Methyl-2-hydroxypropionamide 13027-88-8
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-19
- Product
- 2-Methyl-2-hydroxypropionamide 13027-88-8
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.8%
- Supply Ability
- 100tons
- Release date
- 2024-08-16
- Product
- 2-Methyl-2-hydroxypropionamide 13027-88-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11