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HA PEPTIDE

Product Name
HA PEPTIDE
CAS No.
92000-76-5
Chemical Name
HA PEPTIDE
Synonyms
YPYDVPDYA;HA PEPTIDE;HA TAG PEPTIDE;H2N-YPYDVPDYA-OH;HA1 FRAGMENT 99-107;HA Peptide (HA tag);HA1 fragment 98-106;HA PEPTIDE USP/EP/BP;5-Trihydroxybibenzyl;TYR-PRO-TYR-ASP-VAL-PRO-ASP-TYR-ALA
CBNumber
CB1232396
Molecular Formula
C53H67N9O17
Formula Weight
1102.17
MOL File
92000-76-5.mol
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HA PEPTIDE Property

Boiling point:
1556.4±65.0 °C(Predicted)
Density 
1.414±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
-20°C
solubility 
≥55.1 mg/mL in DMSO; ≥100.4 mg/mL in EtOH; ≥46.2 mg/mL in H2O
form 
A crystalline solid
pka
3.38±0.10(Predicted)
color 
White to off-white
Sequence
H-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I2149
Product name
Influenza Hemagglutinin (HA) Peptide
Purity
≥97% (HPLC)
Packaging
0.5mg
Price
$98
Updated
2024/03/01
Sigma-Aldrich
Product number
I2149
Product name
Influenza Hemagglutinin (HA) Peptide
Purity
≥97% (HPLC)
Packaging
1mg
Price
$171
Updated
2024/03/01
ChemScene
Product number
CS-7004
Product name
HAPeptide
Purity
99.23%
Packaging
1mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-7004
Product name
HAPeptide
Purity
99.23%
Packaging
5mg
Price
$96
Updated
2021/12/16
ApexBio Technology
Product number
A6004
Product name
Influenza Hemagglutinin (HA) Peptide
Packaging
5mg
Price
$99
Updated
2021/12/16
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HA PEPTIDE Chemical Properties,Usage,Production

Uses

Influenza Hemagglutinin (HA) Peptide may be used in immunoblotting. It may also be used to to elute HA-tagged fusion proteins from an affinity column of Monoclonal Anti-HA agarose.

Definition

ChEBI: HA peptide is a nine amino acid peptide with sequence YPYDVPDYA derived from an epitope of the influenza hemagglutinin protein. It is extensively used as an epitope tag on recombinant proteins to facilitate their isolation, purification, and detection.

General Description

Influenza Hemagglutinin (HA) peptide is a synthetic peptide with an amino acid sequence of N-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-C. This corresponds to amino acids 98-106 of the human influenza virus hemagglutinin. The HA Peptide is used for competing out the anti-HA antibody binding to HA-tagged fusion proteins in immunoassays. The successful inhibition of antibody binding by HA peptide demonstrates binding is specific.

Biological Activity

ha tag,complexes containing plasmid dna, transferrin-polylysine conjugates, and polylysine-conjugated peptides derived from the n-terminal sequence of the influenza virus hemagglutinin subunit ha-2 have been used for the transfer of luciferase or -galactosidase marker genes to k562 cells, hela cells, and bnl cl.2 hepatocytes. the presence of these influenza peptide conjugates in the dna complexes renders the complexes active in membrane disruption in a liposome leakage assay and results in a substantial augmentation of the transferrin-polylysine-mediated gene transfer.fusogenic peptides derived from the n-terminal sequence of the influenza virus hemagglutinin subunit ha-2 is part of the dna complexes and the resulting augmentation of gene transfer to cultured cells1.in the influenza virus, the hemagglutinin (ha) protein mediates both binding of the virus to the cell surface and the subsequent fusion of viral and cellular membranes. ha is composed of a receptor-binding subunit, denoted ha1, and a fusogenic subunit, denoted ha2. the native ha1yha2 complex, as found on the surface of the native virus, is fusioninactive. for influenza virus, membrane fusion is regulated by the conformational state of the hemagglutinin (ha) protein, which switches from a native (nonfusogenic) structure to a fusion-active (fusogenic) conformation when exposed to the acidic environment of the cellular endosome. the native structure of ha is trapped in a metastable state and that the fusogenic conformation is released by destabilization of native structure2.

References

1. e. wagner, c. plank et al, influenza virus hemagglutinin ha-2 n-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-dna complexes: toward a synthetic virus-like gene-transfer vehicle. proc. nati. acad. sci. usa vol. 89, pp. 7934-7938, september 1992 2. c. m. carr, c. chaudhry, p. s. kim et al. influenza hemagglutinin is spring-loaded by a metastable native conformation. proc. natl. acad. sci. usa vol. 94, pp. 14306–14313

HA PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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HA PEPTIDE Suppliers

China 109 Europe 2 Germany 1 Switzerland 1 United States 19 Global 132
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
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58
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
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58
ApexBio Technology LLC
Tel
+1-832-696-8203
Fax
+1-832-641-3177
Email
info@apexbt.com
Country
United States
ProdList
477
Advantage
60
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
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58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
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58
ApexBio Technology
Tel
--
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sales@apexbt.com
Country
United States
ProdList
6251
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58
Aroz Technologies, LLC.
Tel
--
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sales@aroztech.com
Country
United States
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1877
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Abcam
Tel
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Email
us.orders@abcam.com
Country
United States
ProdList
6000
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50
Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
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81
MedChemExpress
Tel
--
Fax
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Email
sales@medchemexpress.com
Country
United States
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6398
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Riedel-de Haen AG
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6773
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3B Scientific Corporation
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United States
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LKT Laboratories, Inc.
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2164
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AnaSpec, Inc.
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service@anaspec.com
Country
United States
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4871
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Roche Applied Science
Tel
--
Fax
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Email
biochemts.us@roche.com
Country
United States
ProdList
696
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85
New England Peptide, Inc.
Tel
--
Fax
--
Email
tech@newenglandpeptide.com
Country
United States
ProdList
557
Advantage
71
GenScript Corporation
Tel
--
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Email
info@genscript.com
Country
United States
ProdList
400
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View Lastest Price from HA PEPTIDE manufacturers

Career Henan Chemical Co
Product
HA PEPTIDE 92000-76-5
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

92000-76-5, HA PEPTIDERelated Search:

HA PEPTIDE

  • INFLUENZA HEMAGGLUTININ (HA) PEPTIDE
  • H-TYR-PRO-TYR-ASP-VAL-PRO-ASP-TYR-ALA-OH
  • HA Peptide (HA tag)
  • Influenza hemagglutinin (HA) peptide, ≥97% (HPLC)
  • HEMAGGLUTININ PRECURSOR (114-122) [INFLUENZA A VIRUS]
  • HA1 FRAGMENT 99-107
  • H2N-YPYDVPDYA-OH
  • HA TAG PEPTIDE
  • HA PEPTIDE
  • TYR-PRO-TYR-ASP-VAL-PRO-ASP-TYR-ALA
  • YPYDVPDYA
  • HA tag peptide, HA1 fragment 98-106, Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala
  • HA1 fragment 98-106
  • L-Alanine,L-tyrosyl-L-prolyl-L-tyrosyl-L-a-aspartyl-L-valyl-L-prolyl-L-a-aspartyl-L-tyrosyl-
  • L-Alanine, L-tyrosyl-L-prolyl-L-tyrosyl-L-α-aspartyl-L-valyl-L-prolyl-L-α-aspartyl-L-tyrosyl-
  • HA PEPTIDE USP/EP/BP
  • 5-Trihydroxybibenzyl
  • Influenza Hemagglutinin Peptide (trifluoroacetate salt)
  • E2971 Influenza Hemagglutinin (HA) Peptide
  • 92000-76-5
  • C53H67N9O17
  • Protein Purification
  • Plant Proteomics
  • Plant Biotechnology
  • Additional Affinity Purification
  • BioChemical
  • EpitopeTags
  • Peptide