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4-(2-BOC-AMINOETHYL)BENZOIC ACID

Product Name
4-(2-BOC-AMINOETHYL)BENZOIC ACID
CAS No.
132690-91-6
Chemical Name
4-(2-BOC-AMINOETHYL)BENZOIC ACID
Synonyms
4-(2-BOC-AMINOETHYL)BENZOIC ACID;4-(2-Boc-aminoethyl)benzoic acid;4-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]benzoic acid;Benzoic acid, 4-[2-[[(1,1-diMethylethoxy)carbonyl]aMino]ethyl]-
CBNumber
CB1241024
Molecular Formula
C14H19NO4
Formula Weight
265.3
MOL File
132690-91-6.mol
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4-(2-BOC-AMINOETHYL)BENZOIC ACID Property

Boiling point:
440.5±38.0 °C(Predicted)
Density 
1.155±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.31±0.10(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B809888
Product name
4-(2-((tert-Butoxycarbonyl)amino)ethyl)benzoicAcid
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
056447
Product name
4-(2-{[(tert-Butoxy)carbonyl]amino}ethyl)-benzoic acid
Purity
>95%
Packaging
500mg
Price
$244
Updated
2021/12/16
AK Scientific
Product number
X9841
Product name
4-(2-Boc-aminoethyl)benzoicacid
Packaging
5g
Price
$272
Updated
2021/12/16
Matrix Scientific
Product number
056447
Product name
4-(2-{[(tert-Butoxy)carbonyl]amino}ethyl)-benzoic acid
Purity
>95%
Packaging
1g
Price
$304
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0068602
Product name
4-(2-([(TERT-BUTOXY)CARBONYL]AMINO)ETHYL)BENZOIC ACID
Purity
95.00%
Packaging
500MG
Price
$720.84
Updated
2021/12/16
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4-(2-BOC-AMINOETHYL)BENZOIC ACID Chemical Properties,Usage,Production

Synthesis

24424-99-5

1199-69-5

132690-91-6

10A: 4-(2-aminoethyl)benzoic acid (200 mg, 0.99 mmol) and di-tert-butyl dicarbonate (260 mg, 1.2 mmol) were dissolved in 1 mL of 1 M NaOH aqueous solution. The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, ethyl acetate was added followed by 10% aqueous citric acid solution. A white solid precipitate was observed, which was separated by filtration. The filtrate was extracted three times with ethyl acetate. The combined organic layers were washed sequentially with water and brine, dried over anhydrous Na2SO4 and concentrated under reduced pressure. The residue was purified by rapid chromatography on silica gel with the eluent CH2Cl2/MeOH (100:0 to 95:5). A white solid product (47 mg, 16% yield) was obtained.1H NMR (CDCl3, ppm): δ 1.33 (s, 9H), 2.74 (t, J = 7.44 Hz, 2H), 3.14 (q, J = 6.78 Hz, 2H), 6.84 (br t, J = 5.43 Hz, 1H), 7.28 (d, J = 8.28 Hz, 2H ), 7.83 (d, J = 8.25 Hz, 2H).

References

[1] Patent: WO2012/3544, 2012, A1. Location in patent: Page/Page column 55
[2] Journal of Pharmacology and Experimental Therapeutics, 2008, vol. 324, # 1, p. 206 - 213
[3] Journal of Nanoscience and Nanotechnology, 2012, vol. 12, # 6, p. 5030 - 5038
[4] Patent: US2015/31673, 2015, A1. Location in patent: Paragraph 0409; 0410

4-(2-BOC-AMINOETHYL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-BOC-AMINOETHYL)BENZOIC ACID Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
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Cool Pharm, Ltd
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View Lastest Price from 4-(2-BOC-AMINOETHYL)BENZOIC ACID manufacturers

Honest Joy Holdings Limited
Product
4-(2-Boc-aminoethyl)benzoic acid 132690-91-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99.4%
Supply Ability
100 tons
Release date
2022-01-25