ChemicalBook > CAS DataBase List > 2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID

Product Name: 2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID
CAS No.: 37102-48-0
Chemical Name: 2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID
Synonyms: 2-Methyl-3-pyrrolecarboxylic acid;2-Methylpyrrole-3-carboxylic acid;2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID;1H-Pyrrole-3-carboxylic acid, 2-Methyl-;2-Methyl-1H-Pyrrole-3-Carboxylic Acid(WX614100)
CBNumber: CB12446698
Molecular Formula: C6H7NO2
Formula Weight: 125.13
MOL File: 37102-48-0.mol

Less

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID Property

Melting point:: 178-179℃
Boiling point:: 322.4±22.0 °C(Predicted)
Density: 1.295
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 5.60±0.50(Predicted)
Appearance: Light brown to brown Solid
InChI: InChI=1S/C6H7NO2/c1-4-5(6(8)9)2-3-7-4/h2-3,7H,1H3,(H,8,9)
InChIKey: YBJBJOLFTYIFKP-UHFFFAOYSA-N
SMILES: N1C=CC(C(O)=O)=C1C

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CBR01791
Product name: 2-Methyl-1H-pyrrole-3-carboxylic acid
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2025/07/31

TRC

Product number: M308600
Product name: 2-Methyl-1H-pyrrole-3-carboxylic acid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M308600
Product name: 2-Methyl-1H-pyrrole-3-carboxylic acid
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Usbiological

Product number: 283753
Product name: 2-Methyl-1H-pyrrole-3-carboxylic acid
Packaging: 100mg
Price: $382
Updated: 2021/12/16

ChemScene

Product number: CS-0038738
Product name: 2-Methyl-1H-pyrrole-3-carboxylic acid
Purity: 96.27%
Packaging: 1g
Price: $57
Updated: 2021/12/16

Less

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

2-Methyl-1H-Pyrrole-3-carboxylic acid was examined for its inhibitory properties of BET bromodomains. 2-Methyl-1H-Pyrrole-3-carboxylic acid is also patented as a plant-growth regulator.

Synthesis

936-12-9

37102-48-0

Example 149a Synthesis of 2-methyl-1H-pyrrole-3-carboxylic acid: an aqueous solution (20 mL) of lithium hydroxide (1.563 g, 65.3 mmol) was added to a solution of dioxane (20 mL) containing ethyl 2-methyl-1H-pyrrole-3-carboxylate (2.0 g, 13.06 mmol). The reaction mixture was heated under reflux conditions for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently extracted by partitioning with ethyl acetate and 1 M hydrochloric acid. The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target compound 2-methyl-1H-pyrrole-3-carboxylic acid (1.513 g, 93% yield).

References

[1] Patent: US2014/275079, 2014, A1. Location in patent: Paragraph 0604
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 29, p. 7911 - 7914
[3] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 10, p. 2225 - 2233
[4] Chemische Berichte, 1911, vol. 44, p. 490
[5] Chemische Berichte, 1918, vol. 51, p. 569

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID Suppliers

China 52 Germany 1 India 1 Ukraine 2 United Kingdom 1 United States 8 Global 65

Alichem(Changzhou) Co., Ltd.

Tel: 19941333411
Fax: QQ:749741756
Email: sales@alichem.cn
Country: China
ProdList: 523
Advantage: 58

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Yancheng Orgunion Pharmaceutical Sci & Tech Co., Ltd.

Tel: 0515-89701588 13770166955
Fax: 0515-87400189
Email: orgunion@orgunion.com
Country: China
ProdList: 620
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Sense Chemicals (Shanghai) Co., Ltd.

Tel: +86 13590492756
Fax: +86 (0)21 57626234
Email: michael.he@sensechemicals.com
Country: China
ProdList: 426
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Shanghai XR Chemical Technology Co., Ltd.

Tel: 021-31007982 18019432809
Fax: 021-31007982
Email: info@xrpharma.com
Country: China
ProdList: 676
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Jiangsu Mingchem Corporation

Tel: 0519-85170101
Fax: 0519-85170505
Email: sales@mingchem.com
Country: China
ProdList: 608
Advantage: 55

Shanghai Universe International trade Co.,Ltd

Tel: 17317567081
Email: info@coreuni.com
Country: China
ProdList: 201
Advantage: 55

Zhengzhou AiXi Technology Co., Ltd.

Tel: 0371-56787280 13137706083
Fax: -
Email: m18539565376@163.com
Country: China
ProdList: 970
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22345
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Suzhou Rovathin Foreign Trade Co.,Ltd

Tel: 0512-65816829 18662214788
Fax: 0512-65816829
Email: info@rovathin.com.cn
Country: China
ProdList: 9987
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Zhejiang Lianshuo Biotechnology Co., Ltd.

Tel: 18616526224
Email: lianshuo@vip.126.com
Country: China
ProdList: 9607
Advantage: 58

LEADMEDPHARM CO.,LTD

Tel: 13674959855 13674959855
Email: sales@synthontech.com
Country: China
ProdList: 3035
Advantage: 58

Block Chemical Technology (Shanghai) Co., LTD

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 9673
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

Xinyi Guangbang Medical Technology Co., Ltd.

Tel: 13361936468
Email: 410756539@qq.com
Country: China
ProdList: 306
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9991
Advantage: 58

Hubei Co-prosperity Medicine Technonlogy Co., Ltd

Tel: 2383948258 19172820304
Email: 2383948258@qq.com
Country: China
ProdList: 12987
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 15870833005
Email: 2232044025@qq.com
Country: China
ProdList: 8206
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Suzhou Meishi Biotechnology Co., Ltd.

Tel: 1173954148q
Email: meishipharma@126.com
Country: China
ProdList: 20033
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: syeu@accelachem.com
Country: China
ProdList: 11015
Advantage: 58

Sichuan Boyou Biotechnology Co., Ltd

Tel: 028-65791793 18140026355
Email: 568470422@qq.com
Country: China
ProdList: 9458
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49941
Advantage: 58

PT CHEM GROUP LIMITED

Tel: +86-85511178;
Email: peter68@ptchemgroup.com
Country: China
ProdList: 35425
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Guangzhou Yankexin Biotechnology Co., Ltd.

Tel: 19582413149
Country: CHINA
ProdList: 113
Advantage: 58

Guangzhou Keyu Biotechnology Co., Ltd.

Tel: 18818657868
Country: CHINA
ProdList: 0
Advantage: 58

Guangzhou Jinling Biotechnology Co., Ltd.

Tel: 15017560539
Country: CHINA
ProdList: 142
Advantage: 58

37102-48-0, 2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACIDRelated Search:

3-CARBOXY-1,4-DIMETHYL-1H-PYRROLE-2-ACETIC ACID 2-CARBOXYMETHYL-1-METHYLPYRROLE-3-CARBOXYLIC ACID 4-(Ethoxycarbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylic acid 2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate Diethyl 2,4-dimethylpyrrole-3,5-dicarboxylate Ethyl2,5-dimethylpyrrole-3-carboxylate 3,5-DIMETHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID 2-ETHYL ESTER 4-BENZYL 2-ETHYL 3-(2-ETHOXY-2-OXOETHYL)-5-METHYL-1H-PYRROLE-2,4-DICARBOXYLATE DIMETHYL INDOLE-2,3-DICARBOXYLATE 2,5-DIMETHYL-1-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID 5-FORMYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE 2-BENZYL 4-ETHYL 3,5-DIMETHYL-1H-PYRROLE-2,4-DICARBOXYLATE ETHYL-1-BENZYL-2,4-DIMETHYLPYRROLE-3-CARBOXYLATE ZERENEX E/5030028 5-BROMOMETHYL-3-METHYL-1H-PYRROLE-2,4-DICARBOXYLIC ACID DIETHYL ESTER ETHYL 4,5-DIPHENYL-2-METHYL-3-PYRROLECARBOXYLATE

2-METHYL-1H-PYRROLE-3-CARBOXYLIC ACID

2-Methylpyrrole-3-carboxylic acid

1H-Pyrrole-3-carboxylic acid, 2-Methyl-

2-Methyl-1H-Pyrrole-3-Carboxylic Acid(WX614100)

2-Methyl-3-pyrrolecarboxylic acid

37102-48-0