1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE

Product Name: 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
CAS No.: 301648-08-8
Chemical Name: 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
Synonyms: UCB 35625;1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE
CBNumber: CB12453443
Molecular Formula: C30H37Cl2N2O2.I
Formula Weight: 655.44
MOL File: 301648-08-8.mol

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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Property

storage temp.: Store at +4°C
solubility: <32.77mg/ml in ethanol; <65.54mg/ml in DMSO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2757
Product name: UCB35625
Purity: ≥98%(HPLC)
Packaging: 1
Price: $147
Updated: 2021/12/16

Tocris

Product number: 2757
Product name: UCB35625
Purity: ≥98%(HPLC)
Packaging: 10
Price: $311
Updated: 2021/12/16

Usbiological

Product number: 257011
Product name: UCB 35625
Packaging: 1mg
Price: $380
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001210
Product name: UCB 35625
Purity: 95.00%
Packaging: 5MG
Price: $500.97
Updated: 2021/12/16

ApexBio Technology

Product number: B7176
Product name: UCB35625
Packaging: 1mg
Price: $218
Updated: 2021/12/16

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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Chemical Properties,Usage,Production

Uses

UCB 35625 is an antagonist of CCR1, which are receptors prevalent in chronic inflammatory processes. UCB 35625 displays antiarthritic activity and is also a selective antagonist of CCR3.

Biological Activity

Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 α -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC 50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC 50 = 57 nM). Isomer of J 113863 (1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ).

1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE Suppliers

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301648-08-8, 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDERelated Search:

TRIMETHYLNONYLAMMONIUMIODIDE ALLYLTRIETHYLAMMONIUM IODIDE XANTHENE-9-CARBOXAMIDE XANTHENE-9-METHYLAMINE 1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE

1,4-TRANS-1-(1-CYCLOOCTEN-1-YLMETHYL)-4-[[(2,7-DICHLORO-9H-XANTHEN-9-YL)CARBONYL]AMINO]-1-ETHYLPIPERIDINIUM IODIDE

UCB 35625

301648-08-8

C30H37Cl2IN2O2