2-BROMO-6-(CHLOROMETHYL)PYRIDINE

Product Name: 2-BROMO-6-(CHLOROMETHYL)PYRIDINE
CAS No.: 727356-19-6
Chemical Name: 2-BROMO-6-(CHLOROMETHYL)PYRIDINE
Synonyms: 2-BROMO-6-(CHLOROMETHYL)PYRIDINE;Pyridine, 2-bromo-6-(chloromethyl)-
CBNumber: CB12454455
Molecular Formula: C6H5BrClN
Formula Weight: 206.47
MOL File: 727356-19-6.mol

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2-BROMO-6-(CHLOROMETHYL)PYRIDINE Property

Boiling point:: 262.5±25.0 °C(Predicted)
Density: 1.631±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -0.73±0.12(Predicted)
Appearance: White to off-white Solid

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 5484AJ
Product name: 2-Bromo-6-(chloromethyl)pyridine
Packaging: 250mg
Price: $150
Updated: 2021/12/16

Matrix Scientific

Product number: 118800
Product name: 2-Bromo-6-(chloromethyl)pyridine
Purity: >97%
Packaging: 500mg
Price: $205
Updated: 2021/12/16

Apolloscientific

Product number: OR311109
Product name: 2-Bromo-6-(chloromethyl)pyridine
Packaging: 500mg
Price: $211
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-D-3B
Product name: 2-Bromo-6-(chloromethyl)pyridine
Packaging: 500mg
Price: $232
Updated: 2021/12/16

Matrix Scientific

Product number: 118800
Product name: 2-Bromo-6-(chloromethyl)pyridine
Purity: >97%
Packaging: 1g
Price: $279
Updated: 2021/12/16

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2-BROMO-6-(CHLOROMETHYL)PYRIDINE Chemical Properties,Usage,Production

Synthesis

33674-96-3

727356-19-6

Step 1: Preparation of 2-bromo-6-(chloromethyl)pyridine 6-Bromopyridine-2-methanol (5.00 g, 25.5 mmol) was dissolved in chloroform (30 ml), thionyl chloride (2.8 ml, 38.3 mmol) was added slowly and the reaction was stirred for 3 hours at room temperature. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue was neutralized by adding saturated aqueous sodium bicarbonate solution, and the precipitate was collected by filtration. After washing the precipitate with water, it was dried under vacuum to obtain white solid 2-bromo-6-(chloromethyl)pyridine (5.20 g, 99% yield).

References

[1] Patent: US2006/205731, 2006, A1. Location in patent: Page/Page column 52
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 23, p. 8421 - 8439
[3] Patent: WO2009/120789, 2009, A1. Location in patent: Page/Page column 80; 81
[4] Patent: WO2007/88999, 2007, A1. Location in patent: Page/Page column 115-116
[5] Patent: WO2008/73461, 2008, A2. Location in patent: Page/Page column 132; 133

2-BROMO-6-(CHLOROMETHYL)PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-6-(CHLOROMETHYL)PYRIDINE Suppliers

China 47 India 1 United Kingdom 1 United States 4 Global 53

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727356-19-6, 2-BROMO-6-(CHLOROMETHYL)PYRIDINERelated Search:

2-BROMO-6-(BROMOMETHYL)PYRIDINE Picoxystrobin Pentachloropyridine 2-BROMO-6-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE 2-BROMO-6-(CHLOROMETHYL)PYRIDINE

2-BROMO-6-(CHLOROMETHYL)PYRIDINE

Pyridine, 2-bromo-6-(chloromethyl)-

727356-19-6