ChemicalBook > CAS DataBase List > (S)-2-AMINOHEX-5-YNOIC ACID

(S)-2-AMINOHEX-5-YNOIC ACID

Product Name
(S)-2-AMINOHEX-5-YNOIC ACID
CAS No.
98891-36-2
Chemical Name
(S)-2-AMINOHEX-5-YNOIC ACID
Synonyms
H-Abu(ethynyl)-OH;L-HOMOPROPARGYLGLYCINE;H-HoMoGly(Propargyl)-OH;L-HomoGly(Propargyl)-OH;(S)-2-Aminohex-5-ynoicaci;(S)-2-Amino-5-hexynoic acid;(S)-2-AMINOHEX-5-YNOIC ACID;HPG(L-Homopropargylglycine);(2S)-2-Amino-5-hexynoic acid;(2S)-2-aminohex-5-ynoic acid
CBNumber
CB12455715
Molecular Formula
C6H9NO2
Formula Weight
127.14
MOL File
98891-36-2.mol
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(S)-2-AMINOHEX-5-YNOIC ACID Property

Melting point:
162°C
Boiling point:
260.5±35.0 °C(Predicted)
Density 
1.155±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Aqueous Acid (Sparingly), Methanol (Slightly), Water (Slightly)
form 
powder or crystals
pka
2.21±0.10(Predicted)
color 
White to Off-White
Appearance
off-white solid
Stability:
Hygroscopic
CAS DataBase Reference
98891-36-2
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Safety

HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900893
Product name
L-Homopropargylglycine hydrochloride
Packaging
100MG
Price
$257
Updated
2023/06/20
Cayman Chemical
Product number
11785
Product name
L-Homopropargyl Glycine
Purity
≥98%
Packaging
5mg
Price
$25
Updated
2021/12/16
Cayman Chemical
Product number
11785
Product name
L-Homopropargyl Glycine
Purity
≥98%
Packaging
10mg
Price
$45
Updated
2021/12/16
Cayman Chemical
Product number
11785
Product name
L-Homopropargyl Glycine
Purity
≥98%
Packaging
50mg
Price
$175
Updated
2021/12/16
Cayman Chemical
Product number
11785
Product name
L-Homopropargyl Glycine
Purity
≥98%
Packaging
100mg
Price
$300
Updated
2021/12/16
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(S)-2-AMINOHEX-5-YNOIC ACID Chemical Properties,Usage,Production

Description

L-Homopropargylglycine (HPG) is a noncanonical amino acid analog of methionine that contains a terminal alkyne moiety. HPG-labeling is a fast, sensitive, non-toxic, and non-radioactive alternative to the traditional technique for detecting nascent protein synthesis.


HPG is the cell-permeable compound randomly incorporated into synthesizing protein instead of methionine during translation. The resulting alkyne-labeled full-length proteins can be detected via copper-catalyzed click reaction with fluorescent or biotin-labeled azides and used for subsequent microscopic imaging or purification tasks.

Uses

L-Homopropargyl glycine is a reactive methionine analog that contains an alkyne moiety. It is readily inserted into newly-synthesized proteins in place of methionine. L-Homopropargyl glycine can then be labeled or captured through click chemistry. This approach represents a fast, sensitive, and non-radioactive alternative to [35S]-methionine for the detection of nascent protein synthesis.

Uses

L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click” reaction between an azide and an alkyne or cyclooctyne. For example the alkyne-modified protein can be detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

IC 50

Alkyl-Chain

(S)-2-AMINOHEX-5-YNOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (S)-2-AMINOHEX-5-YNOIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(S)-2-AMINOHEX-5-YNOIC ACID 98891-36-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27

98891-36-2, (S)-2-AMINOHEX-5-YNOIC ACIDRelated Search:


  • (S)-2-AMINOHEX-5-YNOIC ACID
  • L-HOMOPROPARGYLGLYCINE
  • H-HoMoGly(Propargyl)-OH
  • (S)-2-Amino-5-hexynoic acid
  • L-Homopropargylglycine (HPG)
  • L-Homopropargylglycine (L-HPG)
  • H-Abu(ethynyl)-OH
  • (2S)-2-aminohex-5-ynoic acid
  • 5-Hexynoic acid, 2-amino-, (2S)-
  • (S)-2-Aminohex-5-ynoicaci
  • (2S)-2-Amino-5-hexynoic acid
  • HPG(L-Homopropargylglycine)
  • L-HomoGly(Propargyl)-OH
  • <sc>L</sc>-Homopropargylglycine hydrochloride
  • MCE,L-Homopropargylglycine,≥98.0%
  • 98891-36-2
  • Unusual Amino Acids