ChemicalBook > CAS DataBase List > PGD-M

PGD-M

Product Name: PGD-M
CAS No.: 133161-96-3
Chemical Name: PGD-M
Synonyms: PGDM;TETRANOR-PGDM;TETRANOR-PROSTAGLANDIN D METABOLITE;(Z)-9α-11β-dihydroxy-15-oxo-2,3,18.19-tetranorprost-5-ene-1,20-dioic acid;Cyclopentanehexanoic acid, 2-[(2Z)-4-carboxy-2-buten-1-yl]-3,5-dihydroxy-γ-oxo-, (1R,2R,3S,5S)-
CBNumber: CB12456550
Molecular Formula: C16H24O7
Formula Weight: 328.36
MOL File: 133161-96-3.mol

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PGD-M Property

storage temp.: Store at -20°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13454
Product name: PGDM
Purity: ≥90% (mixture)
Packaging: 25μg
Price: $177
Updated: 2024/03/01

Cayman Chemical

Product number: 13454
Product name: PGDM
Purity: ≥90% (mixture)
Packaging: 50μg
Price: $334
Updated: 2024/03/01

Cayman Chemical

Product number: 13454
Product name: PGDM
Purity: ≥90% (mixture)
Packaging: 100μg
Price: $629
Updated: 2024/03/01

TRC

Product number: P294080
Product name: PGD-M
Packaging: 25mg
Price: $13750
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 66672
Product name: PGD-M
Packaging: 10mg
Price: $9950
Updated: 2021/12/16

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PGD-M Chemical Properties,Usage,Production

Description

Prostaglandin D₂ (PGD₂) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD₂ with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD₂.

Uses

Labelled PGD-M

Uses

Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization. It is used as a biomarker to assess endogenous production of PGD2.

Uses

PGD-M is the major urinary metabolite of PGD2 in humans.

References

[1] H. GILES P. L. The biology and pharmacology of PGD2[J]. Prostaglandins, 1988, 35 2: Pages 277-300. DOI: 10.1016/0090-6980(88)90093-7
[2] JASON D. MORROW. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay[J]. Analytical biochemistry, 1991, 193 1: Pages 142-148. DOI: 10.1016/0003-2697(91)90054-w

PGD-M Preparation Products And Raw materials

Raw materials

Preparation Products

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PGD-M Suppliers

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133161-96-3, PGD-MRelated Search:

4-OXOOCTANOIC ACID 4-Ketoundecanoicacid 4-OXONONANOIC ACID PGD-M

TETRANOR-PGDM

TETRANOR-PROSTAGLANDIN D METABOLITE

PGDM

(Z)-9α-11β-dihydroxy-15-oxo-2,3,18.19-tetranorprost-5-ene-1,20-dioic acid

Cyclopentanehexanoic acid, 2-[(2Z)-4-carboxy-2-buten-1-yl]-3,5-dihydroxy-γ-oxo-, (1R,2R,3S,5S)-

133161-96-3

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