6-CHLORO-4-IODOPYRIDIN-3-AMINE

Product Name: 6-CHLORO-4-IODOPYRIDIN-3-AMINE
CAS No.: 351227-42-4
Chemical Name: 6-CHLORO-4-IODOPYRIDIN-3-AMINE
Synonyms: 6-Chloro-4-iodo-3-pyridinamine;6-CHLORO-4-IODOPYRIDIN-3-AMINE;3-Amino-6-chloro-4-iodopyridine;3-amino-4-iododine-6-clopyridine;3-Pyridinamine, 6-chloro-4-iodo-;(6-Chloro-4-iodopyridin-3-yl)amine;6-chloro-4-iodopyridin-3-amine - [C86552];6-CHLORO-4-IODOPYRIDIN-3-AMINE ISO 9001：2015 REACH
CBNumber: CB12461109
Molecular Formula: C5H4ClIN2
Formula Weight: 254.46
MOL File: 351227-42-4.mol

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6-CHLORO-4-IODOPYRIDIN-3-AMINE Property

Boiling point:: 359.4±42.0 °C(Predicted)
Density: 2.139±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.60±0.10(Predicted)
form: crystalline powder
color: Faint yellow
InChI: InChI=1S/C5H4ClIN2/c6-5-1-3(7)4(8)2-9-5/h1-2H,8H2
InChIKey: UOICMMKVFPTQMX-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=CC(I)=C1N

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

Apolloscientific

Product number: OR960084
Product name: 6-Chloro-4-iodopyridin-3-amine
Packaging: 250mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-M-0G
Product name: 6-Chloro-4-iodopyridin-3-amine
Packaging: 250mg
Price: $104
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-M-0G
Product name: 6-Chloro-4-iodopyridin-3-amine
Packaging: 1g
Price: $248
Updated: 2021/12/16

Apolloscientific

Product number: OR960084
Product name: 6-Chloro-4-iodopyridin-3-amine
Packaging: 1g
Price: $155
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0367953
Product name: 6-CHLORO-4-IODOPYRIDIN-3-AMINE
Purity: 95.00%
Packaging: 5MG
Price: $499.7
Updated: 2021/12/16

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6-CHLORO-4-IODOPYRIDIN-3-AMINE Chemical Properties,Usage,Production

Synthesis

400777-00-6

351227-42-4

Step c: Synthesis of 6-chloro-4-iodo-pyridin-3-amine Tert-butyl (6-chloro-4-iodo-pyridin-3-yl)-carbamate (10.0 g, 28 mmol) was dissolved in 3 M hydrochloric acid (600 mL), heated to 60°C, and reacted for 12 hours. After completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with saturated sodium bicarbonate solution to 8. Subsequently, the aqueous layer was extracted with ethyl acetate (100 mL × 3). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with the eluent being a petroleum ether solution of 10% ethyl acetate to give 6-chloro-4-iodopyridin-3-amine (6.6 g, 93% yield). 1H-NMR (CDCl3, 400 MHz) δ 7.81 (s, 1H), 7.60 (s, 1H), 4.13 (br s, 2H).

References

[1] Patent: US2009/253736, 2009, A1. Location in patent: Page/Page column 29
[2] Patent: WO2009/151598, 2009, A1. Location in patent: Page/Page column 122-123
[3] Patent: US2002/22624, 2002, A1
[4] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 9, p. 1233 - 1236
[5] Patent: WO2006/59164, 2006, A2. Location in patent: Page/Page column 22

6-CHLORO-4-IODOPYRIDIN-3-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-CHLORO-4-IODOPYRIDIN-3-AMINE Suppliers

China 90 India 1 Switzerland 1 United States 3 Global 95

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
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Email: tcy@tcypharm.com
Country: China
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Energy Chemical

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Shanghai Ennopharm Co., Ltd.

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Beijing Yisiyan Technology Research Center

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Shanghai Topbiochem Technology Co., Ltd

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Shanghai potentpharm CO.,Ltd

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SynAsst Chemical.

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shanghai cooperpharm co.,LTD .

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DONGSHENG CHIRAL PHARMA

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Suzhou Sino Rare Chemical Co., Ltd.

Tel: 0512-62857507
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View Lastest Price from 6-CHLORO-4-IODOPYRIDIN-3-AMINE manufacturers

Dideu Industries Group Limited

Product: 6-CHLORO-4-IODOPYRIDIN-3-AMINE 351227-42-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-06

Career Henan Chemical Co

Product: 6-CHLORO-4-IODOPYRIDIN-3-AMINE 351227-42-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500kg
Release date: 2019-12-31

351227-42-4, 6-CHLORO-4-IODOPYRIDIN-3-AMINERelated Search:

6-CHLORO-4-IODOPYRIDIN-3-AMINE

(6-Chloro-4-iodopyridin-3-yl)amine

3-Pyridinamine, 6-chloro-4-iodo-

6-CHLORO-4-IODOPYRIDIN-3-AMINE ISO 9001：2015 REACH

6-Chloro-4-iodo-3-pyridinamine

3-amino-4-iododine-6-clopyridine

3-Amino-6-chloro-4-iodopyridine

6-chloro-4-iodopyridin-3-amine - [C86552]

351227-42-4