(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one

Uses

Product Name: (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one
CAS No.: 190595-65-4
Chemical Name: (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one
Synonyms: ZTB-7;EZ-ETK;ETMB-06;-3-oxopropyl);-4-(4-(Benzyloxy);EzetiMibe interdiate;Ezetimibe Impurity 17;Ezetimibe Impuriry 17;-3-(3-(4-fluorophenyl);Ezetimibe intermediate 1
CBNumber: CB12462065
Molecular Formula: C31H25F2NO3
Formula Weight: 497.53
MOL File: 190595-65-4.mol

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(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Property

Boiling point:: 706.8±60.0 °C(Predicted)
Density: 1.264
storage temp.: 2-8°C
form: Solid
pka: -0.48±0.60(Predicted)
InChIKey: BVYNXBNCXPJQCW-PQHLKRTFSA-N
SMILES: N1(C2=CC=C(F)C=C2)[C@H](C2=CC=C(OCC3=CC=CC=C3)C=C2)[C@@H](CCC(C2=CC=C(F)C=C2)=O)C1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 091219
Product name: (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
Purity: 95+%
Packaging: 250mg
Price: $246
Updated: 2021/12/16

AK Scientific

Product number: 9915AA
Product name: (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
Packaging: 25g
Price: $514
Updated: 2021/12/16

Matrix Scientific

Product number: 091219
Product name: (3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one
Purity: 95+%
Packaging: 1g
Price: $538
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0036734
Product name: (3R,4S)-4-[4-(BENZYLOXY)PHENYL]-1-(4-FLUOROPHENYL)-3-[3-(4-FLUOROPHENYL)-3-OXOPROPYL]AZETIDIN-2-ONE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0036734
Product name: (3R,4S)-4-[4-(BENZYLOXY)PHENYL]-1-(4-FLUOROPHENYL)-3-[3-(4-FLUOROPHENYL)-3-OXOPROPYL]AZETIDIN-2-ONE
Purity: 95.00%
Packaging: 10G
Price: $1334.03
Updated: 2021/12/16

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(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Chemical Properties,Usage,Production

Uses

4-O-Methylphenyl Ezetimibe-d4 Ketone is an intermediate in the synthesis of Ezetimibe-d4, the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

Uses

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one is used in preparation of ezetimibe and intermediate thereof.

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Suppliers

China 171 India 4 United States 4 Global 179

BOYAN PHARMA

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Email: tanyan@boyanpharma.com
Country: China
ProdList: 109
Advantage: 58

Chemvon Biotechnology Co., Ltd

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Fax: +86-21-50790419
Email: info@chemvon.com
Country: China
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Adamas Reagent, Ltd.

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Fax: 021-64823266
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Country: China
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Anhui Lianchuang Biological Medicine Co.,Ltd

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Email: sales3@lcywhx.com
Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

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XiaoGan ShenYuan ChemPharm co,ltd

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Country: China
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PSN Pharmaceutical Technology Co., Ltd.

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Beijing Isomersyn Technology CO;LTD

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Synches Co., Ltd.

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Changzhou Joyous Chemical Co., Ltd.

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Country: China
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View Lastest Price from (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one manufacturers

Career Henan Chemical Co

Product: (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one 190595-65-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

Shanghai Yingrui Biopharma Co., Ltd.

Product: (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one 190595-65-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100t
Release date: 2018-03-06

190595-65-4, (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-oneRelated Search:

Ezetimibe Impurity 22 Ezetimibe Impurity 32 (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one EzetiMibe (3R,4R,3'S)-IsoMer 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid ent-EzetiMibe 3-O-Acetyl Ezetimibe EzetiMibe LactaM Cleaved Alcohol EzetiMibe Azetidinone Ring-opened IMpurity EZETIMIBE HYDROXY GLUCURONIDE (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 4-[[(4-Fluorophenyl)imino]methyl]-phenol Ulipristal Acetate (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one Ezetimibe Related Impurity 7 ent-Ezetimibe Ketone (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one

E6:synthesis of trans-1-(4-fluorophenyl)-3-[3-oxo-3-(4-fluorophenyl)propyl

2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-[4-(phenylMethoxy)phenyl]-, (3R,4S)-

3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopr

ETMB-06

EzetiMibe interdiate

(3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-o

EZ-ETK

-3-(3-(4-fluorophenyl)

-3-oxopropyl)

-4-(4-(Benzyloxy)

ZTB-7

1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one

(3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-

Ezetimibe Impurity 17

(3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-phenylmethoxyphenyl)azetidin-2-one

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one190595-65-4

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenChemicalbookyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-f...

Benzaldehyde,4-methoxy-8-(phenylmethoxy)-

Acetylchloride,2-[5-(trifluoromethyl)phenoxy]-

Ezetimibe Impuriry 17

(3R,4S)-4-[4- (benzyloxy) phenyl ]-1-(4- fluorophenyl) -3-[3-(4- fluorophenyl) -3- oxopropyl] azetidine -2- one

(3R, 4S) -4- [4- (benzyloxy) phenyl] -1- (4-fluorophenyl) -3- [3- (4-fluorophenyl) -3-oxopropyl] azacyclobutane-2-one

cholesterol-absorption inhibitor Intermediate 2

Cholesterol absorption inhibitor 1

Ezetimibe intermediate 1

(3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one, 99%min

(3R,4S)-4-(4-(Benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)azetidin-2-one - [B89553]

190595-65-4

C31H25F2NO3

Ezetimibe intermediates