OTAVA-BB 1287281
- Product Name
- OTAVA-BB 1287281
- CAS No.
- 81606-47-5
- Chemical Name
- OTAVA-BB 1287281
- Synonyms
- OTAVA-BB 1287281;3-Bromophenyl)-2-methylpropanoicacid;Benzeneacetic acid, 3-broMo-α,α-diMethyl-
- CBNumber
- CB12464731
- Molecular Formula
- C10H11BrO2
- Formula Weight
- 243.1
- MOL File
- 81606-47-5.mol
OTAVA-BB 1287281 Property
- Boiling point:
- 310.8±17.0 °C(Predicted)
- Density
- 1.456±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.22±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B698395
- Product name
- 2-(3-Bromophenyl)-2-methylpropanoicacid
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB143396
- Product name
- 2-(3-Bromophenyl)-2-methylpropanoic acid
- Packaging
- 1g
- Price
- $137
- Updated
- 2021/12/16
- Product number
- Z5153
- Product name
- 2-(3-Bromophenyl)-2-methylpropanoicacid
- Packaging
- 1g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- FB143396
- Product name
- 2-(3-Bromophenyl)-2-methylpropanoic acid
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- Z5153
- Product name
- 2-(3-Bromophenyl)-2-methylpropanoicacid
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
OTAVA-BB 1287281 Chemical Properties,Usage,Production
Synthesis
251458-15-8
81606-47-5
General procedure for the synthesis of 2-(3-bromophenyl)-2-methylpropionic acid from methyl 2-(3-bromophenyl)-2-methylpropionate: Sodium hydroxide solution (2M, 20 mL) was added to a mixture of methanol (20 mL) and tetrahydrofuran (20 mL) of methyl 2-(3-bromophenyl)-2-methylpropionate (6.5 g). The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, the solvent was removed by evaporation and the residue was partitioned between water (100 mL) and dichloromethane (100 mL). The aqueous phase was acidified with 2 M hydrochloric acid and extracted twice with dichloromethane (100 mL and 50 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated under reduced pressure to remove the solvent to afford the target compound 2-(3-bromophenyl)-2-methylpropionic acid (4.55 g, two-step yield 68%) as a milky white solid. NMR hydrogen spectrum (CDCl3) data: δH 7.54 (s, 1H), 7.40 (d, 1H), 7.33 (d, 1H), 7.21 (t, 1H), 1.59 (s, 6H).
References
[1] Patent: WO2010/52448, 2010, A2. Location in patent: Page/Page column 37
[2] Patent: WO2004/48374, 2004, A1. Location in patent: Page 47
OTAVA-BB 1287281 Preparation Products And Raw materials
Raw materials
Preparation Products
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