4-BROMO-3-METHOXYBENZALDEHYDE
- Product Name
- 4-BROMO-3-METHOXYBENZALDEHYDE
- CAS No.
- 43192-34-3
- Chemical Name
- 4-BROMO-3-METHOXYBENZALDEHYDE
- Synonyms
- 135185;3-Methoxy-4-bromobenzaldehyde;4-BROMO-3-METHOXYBENZALDEHYDE;Benzaldehyde, 4-bromo-3-methoxy-;4-Bromo-3-(methoxy-d3)-benzaldehyde
- CBNumber
- CB12465596
- Molecular Formula
- C8H7BrO2
- Formula Weight
- 215.04
- MOL File
- 43192-34-3.mol
4-BROMO-3-METHOXYBENZALDEHYDE Property
- Melting point:
- 126-127℃ (dichloromethane )
- Boiling point:
- 289.7±25.0 °C(Predicted)
- Density
- 1.522±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- crystalline powder
- color
- Faint yellow
- InChI
- InChI=1S/C8H7BrO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-5H,1H3
- InChIKey
- HKLCOMKRVBQSHA-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=C(Br)C(OC)=C1
Safety
- HS Code
- 2913000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B699105
- Product name
- 4-Bromo-3-methoxybenzaldehyde
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- J91613
- Product name
- 4-Bromo-3-methoxybenzaldehyde
- Packaging
- 5g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- OR400178
- Product name
- 4-Bromo-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 2615-9-29
- Product name
- 4-Bromo-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $96
- Updated
- 2021/12/16
- Product number
- OR400178
- Product name
- 4-Bromo-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $279
- Updated
- 2021/12/16
4-BROMO-3-METHOXYBENZALDEHYDE Chemical Properties,Usage,Production
Synthesis
120315-65-3
43192-34-3
The general procedure for the synthesis of 4-bromo-3-methoxybenzaldehyde from 3-methoxy-4-bromobenzonitrile was as follows: to a solution of 4-bromo-3-methoxybenzonitrile (0.38 g, 1.8 mmol) in toluene (25 mL) at -78 °C was slowly added DIBAL-H (1.0 M solution of THF, 3.6 mmol). The reaction temperature was maintained at -78 °C and stirred for 30 min, then gradually warmed to room temperature and continued stirring for 5 h. The reaction was completed by the addition of methanol (1.0 M THF solution). Upon completion of the reaction, methanol (15 mL) was added to quench the reaction and stirring was continued for 30 minutes. Subsequently, 10% aqueous sulfuric acid (10 mL) was added for acidification and extracted with ethyl acetate. The organic layers were combined, dried by adding anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane/ether=4:1) to afford 4-bromo-3-methoxybenzaldehyde in white powder form in 41% yield.
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 1, p. 233 - 249
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 37, p. 9564 - 9569
[3] Patent: KR2017/17173, 2017, A. Location in patent: Paragraph 0078
4-BROMO-3-METHOXYBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-3-METHOXYBENZALDEHYDE manufacturers
- Product
- 4-BROMO-3-METHOXYBENZALDEHYDE 43192-34-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 96%-98%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20