4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER

Product Name: 4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER
CAS No.: 313337-35-8
Chemical Name: 4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER
Synonyms: Methyl 4-Fluoroindole-7-carboxylate;Methyl 4-fluoro-1H-indole-7-carboxylate;4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER;1H-Indole-7-carboxylic acid, 4-fluoro-, Methyl ester
CBNumber: CB12465763
Molecular Formula: C10H8FNO2
Formula Weight: 193.17
MOL File: 313337-35-8.mol

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4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER Property

Boiling point:: 335.6±22.0 °C(Predicted)
Density: 1.341±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 14.82±0.30(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M224010
Product name: Methyl4-Fluoro-1H-indole-7-carboxylate
Packaging: 2mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 125106
Product name: Methyl4-fluoro-1H-indole-7-carboxylate
Purity: 95+%
Packaging: 1g
Price: $1782
Updated: 2021/12/16

AK Scientific

Product number: 3362AB
Product name: Methyl4-fluoro-1H-indole-7-carboxylate
Packaging: 1g
Price: $2455
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0044188
Product name: 4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER
Purity: 95.00%
Packaging: 2G
Price: $2829.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0044188
Product name: 4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER
Purity: 95.00%
Packaging: 5G
Price: $4365.9
Updated: 2021/12/16

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4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

313337-34-7

18107-18-1

313337-35-8

To a suspension of 4-fluoro-7-carboxyindole in a solvent mixture of methanol (18 mL) and benzene (62 mL), (trimethylmethylsilyl) diazomethane (8.8 mL, 17.6 mmol, 2 M hexane solution) was slowly added. The reaction mixture was stirred at room temperature for 30 min, followed by quenching the reaction with excess acetic acid. The reaction solution was concentrated in vacuum and the resulting crude product was purified by fast column chromatography using gradient elution (hexane to 10% ethyl acetate/hexane) as eluent to give the final methyl 4-fluoro-1H-indole-7-carboxylate as a white solid (1.04 g, 83% yield in two steps).

References

[1] Patent: US2004/6090, 2004, A1. Location in patent: Page/Page column 33
[2] Patent: WO2004/11425, 2004, A2. Location in patent: Page 73

4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER Suppliers

China 31 India 1 United States 5 Global 37

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313337-35-8, 4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTERRelated Search:

1H-Indole-7-carboxylic acid, 4-fluoro-, Methyl ester

Methyl 4-fluoro-1H-indole-7-carboxylate

4-FLUORO-7-INDOLE CARBOXYLIC ACID METHYL ESTER

Methyl 4-Fluoroindole-7-carboxylate

313337-35-8