4-(PYRIDIN-3-YLOXY)BENZOIC ACID
- Product Name
- 4-(PYRIDIN-3-YLOXY)BENZOIC ACID
- CAS No.
- 437383-99-8
- Chemical Name
- 4-(PYRIDIN-3-YLOXY)BENZOIC ACID
- Synonyms
- 4-(3-pyridyloxy)benzoic acid;4-(3-pyridinyloxy)Benzoic acid;4-(PYRIDIN-3-YLOXY)BENZOIC ACID;Benzoic acid, 4-(3-pyridinyloxy)-
- CBNumber
- CB12468830
- Molecular Formula
- C12H9NO3
- Formula Weight
- 215.2
- MOL File
- 437383-99-8.mol
4-(PYRIDIN-3-YLOXY)BENZOIC ACID Property
- Boiling point:
- 391.2±22.0 °C(Predicted)
- Density
- 1.298±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 3.98±0.10(Predicted)
- Appearance
- White to off-white Solid
N-Bromosuccinimide Price
- Product number
- P841305
- Product name
- 4-(Pyridin-3-yloxy)benzoicAcid
- Packaging
- 500mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- W6289
- Product name
- 4-(Pyridin-3-yloxy)benzoicacid
- Packaging
- 250mg
- Price
- $162
- Updated
- 2021/12/16
- Product number
- 074546
- Product name
- 4-(Pyridin-3-yloxy)benzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $416
- Updated
- 2021/12/16
- Product number
- CHM0111937
- Product name
- 4-(PYRIDIN-3-YLOXY)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.89
- Updated
- 2021/12/16
- Product number
- CHM0111937
- Product name
- 4-(PYRIDIN-3-YLOXY)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1147.43
- Updated
- 2021/12/16
4-(PYRIDIN-3-YLOXY)BENZOIC ACID Chemical Properties,Usage,Production
Synthesis
877874-61-8
437383-99-8
Step 2. Synthesis of 4-(pyridin-3-yloxy)benzoic acid. Methyl 4-(pyridin-3-yloxy)benzoate (0.8 g) was dissolved in methanol (10 mL) and aqueous sodium hydroxide solution (2 mL) was added. The reaction mixture was stirred at 75°C for 1 hour. Upon completion of the reaction, it was neutralized with 1N hydrochloric acid (10 mL) and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford 4-(pyridin-3-yloxy)benzoic acid (0.8 g, 93% yield) as a white solid. LC-MS analysis showed the molecular ion peak of the target compound m/z: 215 ([M+H]+).
References
[1] Patent: WO2014/176258, 2014, A1. Location in patent: Page/Page column 37
4-(PYRIDIN-3-YLOXY)BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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