Fmoc-norArg(pbf)-OH

Product Name: Fmoc-norArg(pbf)-OH
CAS No.: 1313054-32-8
Chemical Name: Fmoc-norArg(pbf)-OH
Synonyms: Fmoc-norArg(pbf)-OH;(S)-2-(Fmoc-amino)-4-[[amino(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)methylene]amino]butanoic Acid;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)butanoic acid;(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}butanoic acid;(S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(N'-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)formohydrazonamido)butanoic acid;(2S)-4-[[amino-[(2,2,4,6,7-pentamethyl-3~{H}-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)butanoic acid;(2S)-4-[[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid;Butanoic acid, 4-[[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-
CBNumber: CB12470877
Molecular Formula: C33H38N4O7S
Formula Weight: 634.74
MOL File: 1313054-32-8.mol

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Fmoc-norArg(pbf)-OH Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.75±0.10(Predicted)
InChIKey: FWOIXFWITXCUKI-NDEPHWFRSA-N
SMILES: C(O)(=O)[C@@H](NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)CCNC=NNS(C1=C(C)C(C)=C2OC(C)(C)CC2=C1C)(=O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 8413EA
Product name: Fmoc-norArg(Pbf)-OH
Packaging: 100mg
Price: $162
Updated: 2021/12/16

ChemPep

Product number: 180195
Product name: Fmoc-norArg(Pbf)-OH
Packaging: 1g
Price: $400
Updated: 2021/12/16

Iris Biotech GmbH

Product number: FAA8280
Product name: Fmoc-L-Agb(Pbf)-OH
Packaging: 1g
Price: $607.5
Updated: 2021/12/16

Activate Scientific

Product number: AS117539
Product name: Fmoc-norArg(Pbf)-OH
Purity: 97+%
Packaging: 5G
Price: $1134
Updated: 2021/12/16

ChemPep

Product number: 180195
Product name: Fmoc-norArg(Pbf)-OH
Packaging: 5g
Price: $1200
Updated: 2021/12/16

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Fmoc-norArg(pbf)-OH Chemical Properties,Usage,Production

Chemical Properties

The IUPAC Name of Fmoc-norArg(pbf)-OH is rac-(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)propanoic acid. Pbf is 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl.
In addition, conjugation of Arg-containing peptides is difficult due to the steric hindrance of Pbf in a side chain as a protecting group, resulting in low peptide yield or even synthesis failure[1].

References

[1] Keiichi Yamada . “Efficient solid-phase synthesis of cyclic RGD peptides under controlled microwave heating.” Tetrahedron Letters 53 9 (2012): Pages 1066-1070.

Fmoc-norArg(pbf)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-norArg(pbf)-OH Suppliers

China 26 India 1 United States 2 Global 29

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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Aikon International Limited

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Shanghai Jizhi Biochemical Technology Co. Ltd.

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1313054-32-8, Fmoc-norArg(pbf)-OHRelated Search:

(2S)-4-[[amino-[(2,2,4,6,7-pentamethyl-3~{H}-1-benzofuran-5-yl)sulfonylamino]methylidene]amino]-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)butanoic acid

(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{N'-[(2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]carbamimidamido}butanoic acid

Fmoc-norArg(pbf)-OH

Butanoic acid, 4-[[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (2S)-

(2S)-4-[[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]amino]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid

(S,E)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(N'-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)formohydrazonamido)butanoic acid

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(3-((2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)butanoic acid

(S)-2-(Fmoc-amino)-4-[[amino(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamido)methylene]amino]butanoic Acid

1313054-32-8

C33H38N4O7S

amino acid

amino acids