1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

ChemicalBook > CAS DataBase List > 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

Product Name: 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CAS No.: 839713-36-9
Chemical Name: 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Synonyms: APD125;APD-125;APD 125;Nelotanserin;APD125(Nelotanserin);APD125;APD-125;APD 125;APD125; APD-125; APD 125; NELOTANSERIN;1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea;1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
CBNumber: CB12484964
Molecular Formula: C18H15BrF2N4O2
Formula Weight: 437.24
MOL File: 839713-36-9.mol

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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Property

Boiling point:: 425.9±45.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:32.0(Max Conc. mg/mL);73.2(Max Conc. mM)
form: Solid
pka: 12.29±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N389655
Product name: Nelotanserin
Packaging: 5mg
Price: $165
Updated: 2021/12/16

TRC

Product number: N389655
Product name: Nelotanserin
Packaging: 25mg
Price: $670
Updated: 2021/12/16

AK Scientific

Product number: 9867CS
Product name: Nelotanserin
Packaging: 100mg
Price: $549
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB101032
Product name: 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea
Packaging: 50mg
Price: $231
Updated: 2021/12/16

ChemScene

Product number: CS-5984
Product name: Nelotanserin
Purity: 99.79%
Packaging: 25mg
Price: $250
Updated: 2021/12/16

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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Chemical Properties,Usage,Production

Uses

Nelotanserin is a potent selective 5-HT2A inverse agonist, nelotanserin has low nanomolar potency on the 5-HT2A receptor with at least 30- and 5000-fold selectivity compared with 5-HT2C and 5-HT2B receptors.

Definition

ChEBI: Nelotanserin is a member of pyrazoles and a ring assembly.

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea Suppliers

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839713-36-9, 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)ureaRelated Search:

APD125(Nelotanserin)

APD 125

APD125

APD-125

APD125;APD-125;APD 125

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

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Nelotanserin

1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

APD125; APD-125; APD 125; NELOTANSERIN

1-[3-(4-bromo-2-methylpyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea

5-HT Receptor,Inhibitor,APD 125,inhibit,APD-125,Nelotanserin,Serotonin Receptor,5-hydroxytryptamine Receptor

839713-36-9