ChemicalBook > CAS DataBase List > (R)-5-HydroxyMethyl Tolterodine

(R)-5-HydroxyMethyl Tolterodine

Product Name: (R)-5-HydroxyMethyl Tolterodine
CAS No.: 207679-81-0
Chemical Name: (R)-5-HydroxyMethyl Tolterodine
Synonyms: Desfesoterodine;5-HMT;Fesoterodine Diol;5-HM;PNU-200577;PNU 200577;Non Sorodine Impurities;Fesoterodine Diol (R)-Isomer;Desfesoterodine, 10 mM in DMSO;(R)-5-Hydroxymethyl tolterodine
CBNumber: CB12485062
Molecular Formula: C22H31NO2
Formula Weight: 341.49
MOL File: 207679-81-0.mol

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(R)-5-HydroxyMethyl Tolterodine Property

Melting point:: 68-72°C
Boiling point:: 490.7±45.0 °C(Predicted)
Density: 1.060±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.61±0.48(Predicted)
color: Off-White to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: H948363
Product name: (R)-5-HydroxymethylTolterodine
Packaging: 1mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 1g
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 2g
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-0825
Product name: Desfesoterodine
Purity: 99.58%
Packaging: 5mg
Price: $227
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH24399
Product name: (R)-5-Hydroxymethyl tolterodine
Packaging: 5G
Price: $250
Updated: 2021/12/16

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(R)-5-HydroxyMethyl Tolterodine Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

(R)-5-HydroxyMethyl Tolterodine is a metabolite of Tolterodine (T535800), a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Uses

A metabolite of Tolterodine, a muscarinic receptor antagonist used in the treatment of urinary incontinence.

Definition

ChEBI: Desfesoterodine is a diarylmethane.

in vivo

Desfesoterodine (PNU-200577; 5-Hydroxymethyl Tolterodine; 0.1 and 1 mg/kg; IV) significantly increases bladder compliance after moderate and high doses^[4].
In vivo, Desfesoterodine is significantly more potent at suppressing acetylcholine-induced urinary bladder contraction than electrically induced salivation in the anaesthetised cat (ID50=15 and 40 nmol/kg, respectively) ^[1].

Animal Model:	Female Sprague Dawley rats at ages 9 to 11 weeks weighing 180 to 250 g^[4]
Dosage:	0.1 and 1 mg/kg
Administration:	IV; single imidafenacin administration
Result:	Significantly increased bladder compliance after moderate and high doses.

(R)-5-HydroxyMethyl Tolterodine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-5-HydroxyMethyl Tolterodine manufacturers

Career Henan Chemical Co

Product: 3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol 207679-81-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200KG
Release date: 2018-08-06

207679-81-0, (R)-5-HydroxyMethyl TolterodineRelated Search:

Fesoterodine Related Impurity 2 rac 5-Hydroxymethyl Tolterodine, 90% by HPLC Fesoterodine Impurity 6 SPM 907 (S)-(+)-O-Acetyl-L-mandelic acid Deoxy Fesoterodine 3-(3-Aminopropyl)benzoic Acid Hydrochloride Fesoterodine Diol Dimer Benzenepropanol, 2-hydroxy-5-(hydroxyMethyl)-γ-phenyl- FESOTERODINE Fesoterodine Impurity 5 (R)-5-HydroxyMethyl Tolterodine ForMate O-Isobutyryl (R)-Fesoterodine ICOFQCJKJOISKD-HSZRJFAPSA-N Fesoterodine Diol Dimer Monoester SOSXDUQUWXWKQR-OCQXTOTRSA-N Fesoterodine Related Impurity 4 Fesoterodinefumarate

(R)-5-Hydroxymethyl tolterodine

3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxybenzenemethanol

R-(+)-2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenol

5-hydroxyMethyl tolterodine (PNU 200577)

Desfesoterodine

PNU 200577

PNU-200577

(R)-2-(3-(diisopropylaMino)-1-phenylpropyl)-4-(hydroxyMethyl)phenol (5-HMT)

Fesoterodine Diol

5-hydroxyMethyl Tolterodine (PNU 200577, 5-HMT, 5-HM)

Benzenemethanol, 3-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-

Fesoterodine fumarate Intermediate 2

Fesoterodine Impurity 1(Fesoterodine Diol)

2-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol

5-HM

5-HMT

Tolterodine 5-Hydroxymethyl (R)-Isomer

Fesoterodine Diol (R)-Isomer

(R)-5-HydroxyMethyl Tolterodine USP/EP/BP

Tolterodine 5-Hydroxymethyl Analog (R)-Isomer (Fesoterodine Diol (R)-Isomer)

Fesoterodine Diol (R)-Isomer (Tolterodine 5-Hydroxymethyl Analog (R)-Isomer)

2-[(1R)-3-(dipropan-2-ylamino)-1-phenylpropyl]-4-(hydroxymet...

5-Hydroxymethyl TolterodineQ: What is 5-Hydroxymethyl Tolterodine Q: What is the CAS Number of 5-Hydroxymethyl Tolterodine Q: What is the storage condition of 5-Hydroxymethyl Tolterodine Q: What are the applications of 5-Hydroxymethyl Tolterodine

Tolterodine Hydroxymethyl Analog

Desfesoterodine(5-Hydroxymethyl Tolterodine)

Non Sorodine Impurities

(R)-5-HydroxyMethyl Tolterodinel

5-HMT|||(R)-5-Hydroxymethyl Tolterodine|||PNU-200577|||5-HM|||5-hydroxymethyl Tolterodine

Desfesoterodine, 10 mM in DMSO

207679-81-0

07679-81-0

Chiral Reagents

Inhibitors

Intermediates & Fine Chemicals

Metabolites & Impurities

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