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4-(4-bromo-1H-pyrazol-3-yl)pyridine

Product Name
4-(4-bromo-1H-pyrazol-3-yl)pyridine
CAS No.
166196-54-9
Chemical Name
4-(4-bromo-1H-pyrazol-3-yl)pyridine
Synonyms
181179;HDGFRP2/PSIP1-IN-1;4-(4-Bromo-1h-pyrazol-3-yl)pyridin;4-(4-bromo-1H-pyrazol-3-yl)pyridine;Pyridine, 4-(4-bromo-1H-pyrazol-3-yl)-;4-(4-bromo-1H-pyrazol-5-yl)pyridine(SALTDATA: FREE)
CBNumber
CB12485183
Molecular Formula
C8H6BrN3
Formula Weight
224.06
MOL File
166196-54-9.mol
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4-(4-bromo-1H-pyrazol-3-yl)pyridine Property

Boiling point:
381.2±27.0 °C(Predicted)
Density 
1.651
storage temp. 
2-8°C
form 
Solid
pka
10.55±0.50(Predicted)
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B673898
Product name
4-(4-bromo-1H-pyrazol-3-yl)pyridine
Packaging
500mg
Price
$220
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB123868
Product name
4-(4-Bromo-1H-pyrazol-3-yl)pyridine
Packaging
100mg
Price
$58
Updated
2021/12/16
ChemScene
Product number
CS-0060267
Product name
4-(4-Bromo-1H-pyrazol-3-yl)pyridine
Packaging
1g
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB123868
Product name
4-(4-Bromo-1H-pyrazol-3-yl)pyridine
Packaging
250mg
Price
$115
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB123868
Product name
4-(4-Bromo-1H-pyrazol-3-yl)pyridine
Packaging
500mg
Price
$200
Updated
2021/12/16
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4-(4-bromo-1H-pyrazol-3-yl)pyridine Chemical Properties,Usage,Production

Uses

HDGFRP2/PSIP1-IN-1 (compound BPP) is a dual inhibitor targeting the PWWP domain of hepatocarcinogenic growth factor-related protein 2 (HDGFRP2) and its homologous protein PSIP1, hinder the development and progression of diffuse intrinsic pontine glioma (DIPG). HDGFRP2/PSIP1-IN-1 binds to HDGFRP2 with a Kd value of 7 μM and a ligand efficiency of 0.47; it binds to the PSIP1 PWWP domain with a Kd value of 27 μM; meanwhile, it has a Kd value of 14 μM for HDGFRP3, indicating its effectiveness as an inhibitor of the HDGFRP2 PWWP subfamily[1].

References

[1] Xiaoli Wei, et al. Fragment-based discovery of small molecule inhibitors of the HDGFRP2 PWWP domain. FEBS Lett. 2024 Jul 19.1873-3468.14981. DOI:10.1002/1873-3468.14981

4-(4-bromo-1H-pyrazol-3-yl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-bromo-1H-pyrazol-3-yl)pyridine Suppliers

China 46 France 1 India 1 Ukraine 1 United Kingdom 2 United States 7 Global 58
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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China
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Beijing Ouhe Technology Co., Ltd
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010-82967028 13522913783
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+86-10-82967029
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Nan Jing Dirise Chemcial Co.,LTD
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Shanghai Topbiochem Technology Co., Ltd
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Shanghai Run-Biotech Co., Ltd.
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QQ3095748324
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sales@run-biotech.com
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China
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View Lastest Price from 4-(4-bromo-1H-pyrazol-3-yl)pyridine manufacturers

Career Henan Chemical Co
Product
4-(4-bromo-1H-pyrazol-3-yl)pyridine 166196-54-9
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-13

166196-54-9, 4-(4-bromo-1H-pyrazol-3-yl)pyridineRelated Search:

Pyridinium tribromide

  • 4-(4-bromo-1H-pyrazol-3-yl)pyridine
  • 4-(4-bromo-1H-pyrazol-5-yl)pyridine(SALTDATA: FREE)
  • 4-(4-Bromo-1h-pyrazol-3-yl)pyridin
  • Pyridine, 4-(4-bromo-1H-pyrazol-3-yl)-
  • 181179
  • HDGFRP2/PSIP1-IN-1
  • 166196-54-9