exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol

Product Name: exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol
CAS No.: 134575-14-7
Chemical Name: exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol
Synonyms: exo-3-Cbz-3-azabicyclo[3....;exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol;exo-Benzyl 6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate;Benzyl (1R,5S)-6-(hydroxyMethyl)-3-azabicyclo[3.1.0]hexan-3-carboxylate;Benzyl (1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate;benzyl (1S,5R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate;(1alpha,5alpha,6alpha)-3-Cbz-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane;benzyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate;rel-Benzyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate;benzyl rel-(1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
CBNumber: CB12485587
Molecular Formula: C14H17NO3
Formula Weight: 247.29
MOL File: 134575-14-7.mol

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exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol Property

Boiling point:: 400.0±25.0 °C(Predicted)
Density: 1.265±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 14.94±0.10(Predicted)
Appearance: yellow oil
CAS DataBase Reference: 134575-14-7

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B130813
Product name: Benzyl(1R,5S)-6-(Hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

TRC

Product number: B130813
Product name: Benzyl(1R,5S)-6-(Hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
Packaging: 1g
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: Y7446
Product name: Benzyl(1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
Packaging: 250mg
Price: $124
Updated: 2021/12/16

Activate Scientific

Product number: AS12385
Product name: exo-3-Cbz-3-Azabicyclo[3.1.0]hexane-6-methanol
Purity: 97+%
Packaging: 1g
Price: $332
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1052256
Product name: EXO-3-CBZ-3-AZABICYCLO[3.1.0]HEXANE-6-METHANOL
Purity: 95.00%
Packaging: 5MG
Price: $459
Updated: 2021/12/16

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exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol Chemical Properties,Usage,Production

Synthesis

501-53-1

134575-14-7

2. Synthesis of [1α,5α,6α]-3-benzyloxycarbonyl-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexanes Benzyl ester of rel-(1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate (1.0 g, 8.8 mmol) was dissolved in a mixed solvent of dioxane (40 mL) and water (40 mL). Sodium bicarbonate (3 g, 36 mmol) and benzyl chloroformate (1.3 mL, 9.1 mmol) were added sequentially. After 30 min of reaction, the reaction mixture was extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the title compound as an oil (2.15 g, 8.7 mmol, 99% yield). 1H NMR (CDCl3) δ: 7.32 (br s, 5H), 5.08 (s, 2H), 3.65 (m, 2H), 3.46 (m, 4H), 1.45 (m, 2H), 0.91 (m, 1H).

References

[1] Patent: EP413455, 1991, A2
[2] Patent: WO2015/173225, 2015, A1

exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol Preparation Products And Raw materials

Raw materials

Preparation Products

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exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol Suppliers

China 31 India 1 United States 5 Global 37

A.J Chemicals

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Email: sales@ajchem.in
Country: India
ProdList: 6100
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View Lastest Price from exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol manufacturers

Career Henan Chemical Co

Product: exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol 134575-14-7
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-08-05

134575-14-7, exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanolRelated Search:

exo-3-Benzyl-3-azabicyclo[3.1.0]hexane-6-carboxylic acid ethyl ester exo-3-Amino-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid benzyl ester exo-3-AMino-9-Boc-9-azabi... exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-carboxylic acid Methyl exo-3-Boc-3-azabicyclo-[3.1.0]hexane-6-carboxylate

exo-3-Cbz-3-azabicyclo[3.1.0]hexane-6-methanol

exo-3-Cbz-3-azabicyclo[3....

Benzyl (1R,5S)-6-(hydroxyMethyl)-3-azabicyclo[3.1.0]hexan-3-carboxylate

benzyl (1S,5R)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

Benzyl (1R,5S)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

exo-Benzyl 6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

benzyl rel-(1R,5S,6s)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-(hydroxymethyl)-, phenylmethyl ester, (1α,5α,6α)-

benzyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

benzyl rel-(1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

rel-Benzyl (1R,5S,6r)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

Phenylmethyl (1α,5α,6α)-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate

(1alpha,5alpha,6alpha)-3-Cbz-6-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane

134575-14-7