5-Bromo-2-nitro-3-Pyridinol

Product Name: 5-Bromo-2-nitro-3-Pyridinol
CAS No.: 691872-15-8
Chemical Name: 5-Bromo-2-nitro-3-Pyridinol
Synonyms: 5-BroMo-2-nitropyridin-3-ol;5-Bromo-2-nitro-3-Pyridinol;3-Pyridinol, 5-bromo-2-nitro-;5-BroMo-3-hydroxy-2-nitropyridine;Ethanone,1-(2-pyridinyl)-2-(5-quinolinyl)-;5 - bromo - 2 - nitro - 3 - hydroxypyridine;5-Bromo-2-nitro-3-Pyridinol ISO 9001：2015 REACH;1H-Benzimidazole-1-acetonitrile,2,3-dihydro-3-oxo-
CBNumber: CB12488755
Molecular Formula: C5H3BrN2O3
Formula Weight: 218.99
MOL File: 691872-15-8.mol

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5-Bromo-2-nitro-3-Pyridinol Property

Boiling point:: 393.4±37.0 °C(Predicted)
Density: 2.006±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: -1.63±0.10(Predicted)
Appearance: White to light yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B687270
Product name: 5-Bromo-3-hydroxy-2-nitropyridine
Packaging: 5g
Price: $1320
Updated: 2021/12/16

ChemScene

Product number: CS-0060276
Product name: 5-Bromo-2-nitropyridin-3-ol
Purity: >97.0%
Packaging: 100mg
Price: $77
Updated: 2021/12/16

ChemScene

Product number: CS-0060276
Product name: 5-Bromo-2-nitropyridin-3-ol
Purity: >97.0%
Packaging: 250mg
Price: $119
Updated: 2021/12/16

AK Scientific

Product number: 3124AJ
Product name: 5-Bromo-2-nitropyridin-3-ol
Packaging: 100mg
Price: $131
Updated: 2021/12/16

ChemScene

Product number: CS-0060276
Product name: 5-Bromo-2-nitropyridin-3-ol
Purity: >97.0%
Packaging: 1g
Price: $257
Updated: 2021/12/16

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5-Bromo-2-nitro-3-Pyridinol Chemical Properties,Usage,Production

Uses

5-Bromo-3-hydroxy-2-nitropyridine was used to design potent and selective inhibitors to overcome clinical anaplastic Lymphoma kinase mutations resistant to Crizotinib (C785000), a potential antitumor agent.

Synthesis

74115-13-2

691872-15-8

Step 1: Synthesis of 5-bromo-2-nitropyridin-3-ol 3-Bromo-5-hydroxypyridine (2 g, 0.011 mol) was dissolved in concentrated sulfuric acid (6 mL), and fuming nitric acid (0.52 mL, 0.011 mol) was slowly added dropwise under the condition of cooling in an ice bath. After the dropwise addition, the reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the mixture was carefully poured into ice water and stirred thoroughly. The precipitated solid was collected by filtration and washed with cold water to afford the target product 5-bromo-2-nitropyridin-3-ol (2.2 g, 90% yield) in the form of a light yellow solid.

References

[1] Patent: US2012/220551, 2012, A1. Location in patent: Page/Page column 20
[2] Organic Process Research and Development, 2017, vol. 21, # 1, p. 133 - 137
[3] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 17, p. 3636 - 3643

5-Bromo-2-nitro-3-Pyridinol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-nitro-3-Pyridinol Suppliers

China 86 India 2 United States 3 Global 91

Henan Lingbei Biotechnology Co., Ltd

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View Lastest Price from 5-Bromo-2-nitro-3-Pyridinol manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: 5-Bromo-2-nitro-3-pyridinol 691872-15-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-28

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromo-2-nitropyridin-3-ol 691872-15-8
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Shaanxi Dideu New Materials Co. Ltd

Product: 5-Bromo-2-nitro-3-Pyridinol 691872-15-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-31

691872-15-8, 5-Bromo-2-nitro-3-PyridinolRelated Search:

5-Bromo-2-nitro-3-Pyridinol

5-BroMo-2-nitropyridin-3-ol

5-BroMo-3-hydroxy-2-nitropyridine

3-Pyridinol, 5-bromo-2-nitro-

5 - bromo - 2 - nitro - 3 - hydroxypyridine

5-Bromo-2-nitro-3-Pyridinol ISO 9001：2015 REACH

Ethanone,1-(2-pyridinyl)-2-(5-quinolinyl)-

1H-Benzimidazole-1-acetonitrile,2,3-dihydro-3-oxo-

691872-15-8