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2-(4-Amino-1H-pyrazol-1-yl)ethanol

Product Name
2-(4-Amino-1H-pyrazol-1-yl)ethanol
CAS No.
84407-13-6
Chemical Name
2-(4-Amino-1H-pyrazol-1-yl)ethanol
Synonyms
2-(3-Amino-1H-pyrazol-1-yl);2-(3-AMINOPYRAZOL-1-YL)ETHANOL;2-(3-Amino-1-pyrazolyl)ethanol;1H-Pyrazole-1-ethanol, 3-aMino-;2-(4-Amino-1H-pyrazol-1-yl)ethanol;2-(3-AMino-1H-pyrazol-1-yl)ethanol;2-(3-amino-1H-pyrazol-1-yl)ethan-1-ol;2-(4-Amino-1H-pyrazol-1-yl)ethanol (Related Reference)
CBNumber
CB12502677
Molecular Formula
C5H9N3O
Formula Weight
127.14
MOL File
84407-13-6.mol
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2-(4-Amino-1H-pyrazol-1-yl)ethanol Property

Boiling point:
337.9±22.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
14.42±0.10(Predicted)
Appearance
Colorless to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A628983
Product name
2-(3-Amino-1H-pyrazol-1-yl)ethanol
Packaging
100mg
Price
$60
Updated
2021/12/16
Ark Pharm
Product number
P000723355
Product name
2-(3-Amino-1H-pyrazol-1-yl)ethanol
Purity
97%
Packaging
100mg
Price
$22
Updated
2021/12/16
Ark Pharm
Product number
P000723355
Product name
2-(3-Amino-1H-pyrazol-1-yl)ethanol
Purity
97%
Packaging
250mg
Price
$33
Updated
2021/12/16
ChemScene
Product number
CS-W001902
Product name
2-(3-Amino-1H-pyrazol-1-yl)ethanol
Purity
99.84%
Packaging
1g
Price
$76
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA143564
Product name
2-(3-Amino-1H-pyrazol-1-yl)ethanol
Packaging
500mg
Price
$80
Updated
2021/12/16
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2-(4-Amino-1H-pyrazol-1-yl)ethanol Chemical Properties,Usage,Production

Uses

2-(3-Amino-1H-pyrazol-1-yl)ethanol is a reagent in the preparation of pyrazolo pyrimidines with CK2 kinase inhibitory activity.

Synthesis

956951-01-2

84407-13-6

General procedure for the synthesis of 2-(4-amino-1H-pyrazol-1-yl)ethanol from 3-nitro-1H-pyrazol-1-ethanol: 2-(3-nitro-1H-pyrazol-1-yl)ethanol (0.187 g, 1.19 mmol) was dissolved in ethanol (6 mL) and 10% palladium/carbon catalyst (20 mg) was added under argon protection. The reaction mixture was stirred overnight at room temperature and under hydrogen atmosphere (using a hydrogen balloon). Upon completion of the reaction, the insoluble material was removed by filtration through a diatomaceous earth pad and washed with ethanol. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent to give the target product 2-(4-amino-1H-pyrazol-1-yl)ethanol (light brown tar-like substance, 0.151 g, 1.18 mmol, 99% yield).

References

[1] Patent: JP5829520, 2015, B2. Location in patent: Paragraph 0469
[2] Patent: WO2016/180843, 2016, A1. Location in patent: Page/Page column 43
[3] Patent: WO2008/156757, 2008, A1. Location in patent: Page/Page column 234
[4] Patent: US2012/283271, 2012, A1. Location in patent: Page/Page column 11
[5] Patent: WO2013/17479, 2013, A1. Location in patent: Page/Page column 43-44

2-(4-Amino-1H-pyrazol-1-yl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-Amino-1H-pyrazol-1-yl)ethanol Suppliers

China 36 India 1 United Kingdom 1 United States 2 Global 40
QINGDAO CARELONGPHARMATECH CO.,LTD
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0532-0532-88191853 13061484198
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+86-532-88191853
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sales@carelongchem.com
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China
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Shanghai HuanChuan Industry Co.,Ltd.
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021-61478794
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021-61478794
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sales@hcshhai.com
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Shanghai Boyners Pharm-Tech Co., Ltd.
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13817873692
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021-31329586
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mkt@boynerspharm.com
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China
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NovoChemy Ltd.
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Chengdu jingzhihuacheng Chemical Technology Co., Ltd.
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028-028-37664989 15900794981
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Shanghai QianYan Bio-technology Co., Ltd
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orders@biochemsafebuy.com
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Hangzhou Molcore Biopharmatech Co.,Ltd
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400-711-5280 86-571-81025280
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86-571-85806285
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sales@molcore.com
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China
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Sichuan BaiPeng Biotechnology Co., Ltd.
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028-65791793 18140026355
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568470422@qq.com
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Aikon International Limited
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84407-13-6, 2-(4-Amino-1H-pyrazol-1-yl)ethanolRelated Search:


  • 2-(4-Amino-1H-pyrazol-1-yl)ethanol
  • 2-(4-Amino-1H-pyrazol-1-yl)ethanol (Related Reference)
  • 2-(3-Amino-1H-pyrazol-1-yl)
  • 2-(3-AMINOPYRAZOL-1-YL)ETHANOL
  • 1H-Pyrazole-1-ethanol, 3-aMino-
  • 2-(3-AMino-1H-pyrazol-1-yl)ethanol
  • 2-(3-amino-1H-pyrazol-1-yl)ethan-1-ol
  • 2-(3-Amino-1-pyrazolyl)ethanol
  • 84407-13-6