Posaconazole-d4

Product Name: Posaconazole-d4
CAS No.: 1133712-26-1
Chemical Name: Posaconazole-d4
Synonyms: Noxafil-d4;Sch 56592-d4;Posacozole-d5;Posaconazole-d4;Posaconazole A5;[2H4]-Posaconazole;POSACONAZOLE (D4, 98%) 1.0 MG/ML IN METHANOL;Posaconazole D4Q: What is Posaconazole D4 Q: What is the CAS Number of Posaconazole D4 Q: What is the storage condition of Posaconazole D4;2-[(2S,3S)-2-hydroxypentan-3-yl]-4-[2,3,5,6-tetradeuterio-4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one;4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl)piperazin-1-yl](2,3,5,6-2H?)phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one
CBNumber: CB12511512
Molecular Formula: C37H42F2N8O4
Formula Weight: 700.79
MOL File: 1133712-26-1.mol

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Posaconazole-d4 Property

Melting point:: 170-172?C
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
form: Solid
color: Off-White to Light Grey
Stability:: Moisture Sensitive

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P689602
Product name: Posaconazole-d4
Packaging: 1mg
Price: $410
Updated: 2021/12/16

Usbiological

Product number: 019870
Product name: Posaconazole-d4
Packaging: 1mg
Price: $744
Updated: 2021/12/16

ChemScene

Product number: CS-0112159
Product name: Posaconazole-D4
Packaging: 1mg
Price: $350
Updated: 2021/12/16

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Posaconazole-d4 Chemical Properties,Usage,Production

Chemical Properties

Off-White Foam

Uses

Orally active labelled triazole antifungal.

Application

Posaconazole-d4, an isotope of posaconazole, was used as an internal standard and showed retention and ionization identical to those of posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

General Description

This stable-labeled internal standard is suitable for quantification of posaconazole levels in blood, serum, or plasma by HPLC or LC-MS/MS. The antifungal posaconazole is used to treat invasive and systemic fungal infections. As a result of significant drug interactions, therapeutic drug monitoring of posaconazole is recommended when administered with protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Liquid chromatography-mass spectrometry method for the quantification of posaconazole in human plasma: Application to pharmacokinetics following single-dose administration in the fasted state and with a high-fat meal

Posaconazole-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

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1133712-26-1, Posaconazole-d4Related Search:

Posaconazole Impurity 49 Posaconazole Impurity 44 Posaconazole Impurity 17 Posaconazole 1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide Posaconazole Diastereoisomer 11 Posaconazole DiastereoisoMer interMediate 5 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Posaconazole DiastereoisoMer 2 Posaconazole inter-8 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one Posaconazole iMpurity D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- Posaconazole Diastereoisomer 12 Posaconazole DiastereoisoMer interMediate 2 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]- Posaconazole-d5

Posaconazole-d4

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol-d4

Noxafil-d4

Sch 56592-d4

2-[(2S,3S)-2-hydroxypentan-3-yl]-4-[2,3,5,6-tetradeuterio-4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

Posacozole-d5

[2H4]-Posaconazole

POSACONAZOLE (D4, 98%) 1.0 MG/ML IN METHANOL

Posaconazole A5

Posaconazole D4Q: What is Posaconazole D4 Q: What is the CAS Number of Posaconazole D4 Q: What is the storage condition of Posaconazole D4

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl-2,3,5,6-d4)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl)piperazin-1-yl](2,3,5,6-2H?)phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one

1133712-26-1

C37H38D4F2N8O4

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Intermediates & Fine Chemicals

Isotope Labelled Compounds

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