2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Product Name: 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
CAS No.: 503176-50-9
Chemical Name: 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
Synonyms: 3-Fluoro-4-formylphenylboronic acid pinacol ester;3-Fluoro-4-forMylbenzeneboronic acid pinacol ester, 96%;2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde;2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-yl)Benzaldehyde;Benzaldehyde, 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber: CB12513268
Molecular Formula: C13H16BFO3
Formula Weight: 250.07
MOL File: 503176-50-9.mol

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2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Property

storage temp.: Inert atmosphere,2-8°C
form: Solid
Appearance: White to off-white Solid
CAS DataBase Reference: 503176-50-9

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Safety

HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: F591670
Product name: 3-Fluoro-4-formylphenylboronicacidpinacolester
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F591670
Product name: 3-Fluoro-4-formylphenylboronicacidpinacolester
Packaging: 250mg
Price: $50
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: BOR0006404
Product name: 2-FLUORO-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZALDEHYDE
Purity: 95.00%
Packaging: 5MG
Price: $500.1
Updated: 2021/12/16

Matrix Scientific

Product number: 097402
Product name: 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
Purity: 95+%
Packaging: 5g
Price: $588
Updated: 2021/12/16

AK Scientific

Product number: X0870
Product name: 3-Fluoro-4-formylphenylboronicacidpinacolester
Packaging: 1g
Price: $100
Updated: 2021/12/16

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2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Chemical Properties,Usage,Production

Synthesis

57848-46-1

73183-34-3

503176-50-9

In a pressure tube reactor, 4-bromo-2-fluorobenzaldehyde (500 mg, 2.46 mmol), 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bis(1,3,2-dioxaborolane) (938 mg, 3.69 mmol), Pd(dppf)2Cl2 (120 mg, 0.15 mmol), dppf (78 mg, 0.15 mmol) and KOAc (965 mg, 9.84 mmol) were added sequentially. Subsequently, 1,4-dioxane (8 mL) was added as solvent and the reaction was stirred at 85 °C for 13 h under nitrogen protection. Upon completion of the reaction, the reaction mixture was extracted several times with ethyl acetate and water, and the organic layers were combined and dried over anhydrous sodium sulfate to remove water. After concentration under reduced pressure, the product was purified by column chromatography (eluent: 20% ethyl acetate/hexane) to afford the target product 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde in 96% yield. The product was characterized by 1H-NMR (300 MHz, CDCl3): δ 10.38 (s, 1H), 7.85-7.81 (m, 1H), 7.67-7.65 (m, 1H), 7.57 (s, J = 10.4 Hz, 1H), 1.35 (s, 12H).

References

[1] Patent: US2015/259350, 2015, A1. Location in patent: Paragraph 0181; 0182
[2] Patent: KR101745741, 2017, B1. Location in patent: Paragraph 0285

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde Suppliers

China 48 India 2 United States 5 Global 55

A.J Chemicals

Tel: --
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Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

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View Lastest Price from 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde manufacturers

Career Henan Chemical Co

Product: 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 503176-50-9
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%; 99%
Supply Ability: 1kg; 5kg
Release date: 2020-02-03

503176-50-9, 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehydeRelated Search:

3-Fluoro-4-formylphenylboronic acid 2-(3-Fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(3-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol 2-(4-(Bromomethyl)-2-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1-Phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 2-(2-CHLORO-3-METHOXYPHENYL)-4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLANE 4-Chloro-2-methylphenylboronic acid pinacol ester 2-Cyano-4-(trifluoromethyl)phenylboronic acid pinacol ester

2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

3-Fluoro-4-formylphenylboronic acid pinacol ester

Benzaldehyde, 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

3-Fluoro-4-forMylbenzeneboronic acid pinacol ester, 96%

2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane-2-yl)Benzaldehyde

503176-50-9