(S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
Uses- Product Name
- (S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- CAS No.
- 1007882-59-8
- Chemical Name
- (S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- Synonyms
- tert-butyl (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;EOS-61040;(S)-tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-car...;tert-Butyl (S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;(S)-tert-butyl 2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;(S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;tert-butyl (2S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;tert-butyl (2S)-2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate;(S) -2- (5-bromo-1H-imidazo-2-yl) pyrrolidine-1-carboxylate tert butyl ester;(S)-2-(5-bromo-1H-imidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester
- CBNumber
- CB12513859
- Molecular Formula
- C12H18BrN3O2
- Formula Weight
- 316.19
- MOL File
- 1007882-59-8.mol
(S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate Property
- Boiling point:
- 469.3±35.0 °C(Predicted)
- Density
- 1.444±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 11.13±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C12H18BrN3O2/c1-12(2,3)18-11(17)16-6-4-5-8(16)10-14-7-9(13)15-10/h7-8H,4-6H2,1-3H3,(H,14,15)/t8-/m0/s1
- InChIKey
- GAZHEEFWONCMGH-QMMMGPOBSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC[C@H]1C1NC(Br)=CN=1
Safety
- HS Code
- 2933299065
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T135678
- Product name
- (S)-tert-Butyl2-(4-Bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- Packaging
- 1g
- Price
- $330
- Updated
- 2021/12/16
- Product number
- CCH0033491
- Product name
- (S)-TERT-BUTYL-2-(5-BROMO-1H-IMIDAZOL-2-YL)PYRROLIDINE-1-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $376.95
- Updated
- 2021/12/16
- Product number
- 096021
- Product name
- (S)-tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $416
- Updated
- 2021/12/16
- Product number
- Y5844
- Product name
- (S)-tert-Butyl2-(4-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- Packaging
- 250mg
- Price
- $611
- Updated
- 2021/12/16
- Product number
- 1007882598
- Product name
- (S)-tert-Butyl2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
- Packaging
- 10g
- Price
- $787.5
- Updated
- 2021/12/16
(S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate Chemical Properties,Usage,Production
Uses
It can be used as a chemical and pharmaceutical intermediate in the laboratory research and development process.
Synthesis
To a preparation of (S)-tert-butyl 2-(4,5-dibromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (12.5 g, 31.5 mmol) in a mixture of dioxane (400 ml) and H2O (400 ml) was added a solution of Na2SO3 (43.7 g, 347 mmol) in H2O (400 ml) and heated to reflux for 21 hours. The mixture was concentrated to half volume and extracted with CH2Cl2 (3 x 200 ml). The organics were then washed with brine, dried (MgSO4), filtered and concentrated. Purification by grinding (CH2Cl2, tBuOMe, and hexane) afforded 5.2 g (52%) of tert-butyl (S)-2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate. MS (ESI) m/z 317(M+H)+.
(S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate manufacturers
- Product
- (S)-tert-Butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate 1007882-59-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%HPLC
- Supply Ability
- 500kg
- Release date
- 2023-12-01
- Product
- (S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate 1007882-59-8
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24
- Product
- (S)-tert-butyl 2-(5-bromo-1H-imidazol-2-yl)pyrrolidine-1-carboxylate 1007882-59-8
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-24