1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

ChemicalBook > CAS DataBase List > 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

Product Name: 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
CAS No.: 1125812-58-9
Chemical Name: 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone
Synonyms: 1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one;afoxolaner-002;afoxolaner Impurity 6;1-[3-Chloro-5-trifluoromethylphenyl;2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone;3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone;1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone;Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro-
CBNumber: CB12514588
Molecular Formula: C9H3ClF6O
Formula Weight: 276.56
MOL File: 1125812-58-9.mol

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1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Property

Boiling point:: 203℃
Density: 1.512
Flash point:: 77℃
storage temp.: 2-8°C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS146793
Product name: 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
Purity: 95%
Packaging: 1g
Price: $120
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0361882
Product name: 1-(3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL)-2,2,2-TRIFLUOROETHANONE
Purity: 95.00%
Packaging: 0.25G
Price: $243
Updated: 2021/12/16

Ambeed

Product number: A744788
Product name: 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
Purity: 95+%
Packaging: 5g
Price: $255
Updated: 2021/12/16

Crysdot

Product number: CD12179721
Product name: 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
Purity: 95+%
Packaging: 5g
Price: $750
Updated: 2021/12/16

Chemenu

Product number: CM274874
Product name: 1-(3-Chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethanone
Purity: 95+%
Packaging: 500g
Price: $5520
Updated: 2021/12/16

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1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Chemical Properties,Usage,Production

Uses

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Cool the solution containing compound III (74.4g, 0.255mol containing compound III) to -100, and add 120g of sulfuric acid with a mass fraction of 92.5% to the above system while keeping the temperature below 0. After acidification, continue to react and keep for 1.5h, and then add 126.7g of 33% sodium nitrite aqueous solution (containing diazotizing reagent sodium nitrite 0.612mol) into the system uniformly within 2h, and keep the temperature at 0 The following reaction is carried out for 2 hours, and the system is heated to room temperature after full reaction, 111.1 g of 50% hypophosphorous acid and 0.67 g of cuprous oxide are added, and the reaction is stirred for 2 hours while keeping temperature. After the reaction is over, stand to separate the layers, and wash the organic layer with a 5% sodium bicarbonate aqueous solution, dry with anhydrous magnesium sulfate, and rectify to obtain a clear and transparent oily liquid 1-[3-chloro-5-(trifluoromethyl) (Yl)phenyl]-2,2,2-trifluoroethanone 66.9, content 99.5%, yield 87.2%.

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone manufacturers

Hangzhou ICH Biofarm Co., Ltd

Product: 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 98.0% min
Supply Ability: 1ton/month
Release date: 2023-06-09

Career Henan Chemical Co

Product: 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone 1125812-58-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-14

1125812-58-9, 1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanoneRelated Search:

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone

3'-Chloro-5'-trifluoroMethyl-2,2,2-trifluoroacetophenone

2,2,2-trifluoro-3'-chloro-5'-trifluoromethylacetophenone

3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone

1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one

Ethanone, 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoro-

1-(3-chloro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroethan-1-one (Afoxolaner intermediate）

1-[3-Chloro-5-trifluoromethylphenyl]-2,2,2-trifluoroethanone ISO 9001：2015 REACH

afoxolaner-002

afoxolaner Impurity 6

1-[3-Chloro-5-trifluoromethylphenyl

3'-Chloro-5'-trifluoromethoxy-2,2,2-trifluoroacetophenone

1125812-58-9

1123812-58-9