ChemicalBook > CAS DataBase List > DDTT

DDTT

Product Name
DDTT
CAS No.
1192027-04-5
Chemical Name
DDTT
Synonyms
Alternariol-d2;Sulfurizing Reagent II;D447570;Validamycin A (>90%) Disodium Salt;4-Methyl Cannabigerol;AZ 5104 Hydrochloride;70%) Hydrochloride Salt;Elagolix-d6 Sodium Salt;Cetrorelix-D10 TFA Salt
CBNumber
CB12518384
Molecular Formula
C5H7N3S3
Formula Weight
205.32
MOL File
1192027-04-5.mol
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DDTT Property

Melting point:
178-179 °C(Solv: 1,4-dioxane (123-91-1))
Boiling point:
293.9±23.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol (Slightly, Sonicated), Water (Very Slightly, Heated, Sonicated)
pka
-0.21±0.20(Predicted)
form 
Solid
color 
Pale Yellow
Appearance
lemon yellow crystals
Stability:
Very Hygroscopic
InChI
InChI=1S/C5H7N3S3/c1-8(2)3-6-4-7-5(9)11-10-4/h3H,1-2H3
InChIKey
YRDSDHFBUHFDPG-UHFFFAOYSA-N
SMILES
C(N(C)C)=NC1SSC(=S)N=1
CAS DataBase Reference
1192027-04-5
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Safety

HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A637965
Product name
AngiotensinIITrifluoroaceticAcidSalt(Human)
Packaging
25mg
Price
$125
Updated
2021/12/16
TRC
Product number
A630475
Product name
CefdinirThiazineAnalogLactoneForm(MixtureofDiastereomers)
Packaging
5mg
Price
$180
Updated
2021/12/16
TRC
Product number
A634265
Product name
AmoxycilloicAcidTrisodiumSalt(MixtureofDiastereomers)SeeA634268
Packaging
50mg
Price
$1190
Updated
2021/12/16
TRC
Product number
A575771
Product name
AlternariolMonomethylEther-d3
Packaging
10mg
Price
$1455
Updated
2021/12/16
TRC
Product number
A187242
Product name
Nα-Acetyl-L-ornithine-d2
Packaging
25mg
Price
$1890
Updated
2021/12/16
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DDTT Chemical Properties,Usage,Production

Description

DDTT is a sulfurizing reagent used to prepare phosphorothioate linkages, which increase the stability and nuclease resistance of nucleic acids, especially of RNA. It is suitable for automated synthesizers employing standard phosphoramidites for a large-scale synthesis of oligonucleotides.


DDTT demonstrates faster kinetics and higher stability in solution, compared to other sulfurizing reagents such as tetraethylthiuram disulfide (TETD) and Beaucage reagent, respectively. DDTT is commonly applied as a 0.05 M or 0.1 M solution in pyridine/acetonitrile and has a lifetime of up to 6 months.


Coupling: Sulfurization step must come before capping step. The optimum sulfurizing time for DDTT Sulfurizing Reagent, 0.05 M solution in pyridine/acetonitrile: 1 min for DNA or 6 min for RNA.


Deprotection: standard conditions.

Uses

Mugineic Acid, a possible phytosiderophore of graminaceous plants, has iron chelation potency and antioxidant activity.

DDTT Preparation Products And Raw materials

Raw materials

Preparation Products

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DDTT Suppliers

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View Lastest Price from DDTT manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(E)-N,N-dimethyl-N'-(3-sulfanylidene-3H-1,2,4-dithiazol-5-yl)methanimidamide 1192027-04-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
INNOBIO PHARM CO.,LTD
Product
DDTT 1192027-04-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20tons
Release date
2025-01-08
Career Henan Chemical Co
Product
DDTT 1192027-04-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100Kg
Release date
2020-01-03

1192027-04-5, DDTTRelated Search:


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  • (E)-N,N-dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)formimidamide
  • 3-((N,N-dimethylaminomethylidene)amino)-3H-1,2,4-dithiazole-5-thione
  • N,N-Dimethyl-N'-(3-thioxo-3H-1,2,4-dithiazol-5-yl)methanimidamide
  • [(Dimethylamino-methylidene)amino]-3H-1,2,4-dithiazoline-3-thione
  • 5-((dimethylamino-methylidene)amino)-3H-1,2,4,dithiazole-3-thione
  • O-Desmethyl Apixaban Sulfate Sodium Salt
  • 6-O-Methyl Guanosine-d4 (major)
  • (Z)-Triprolidine Dihydrochloride
  • Rupatadine (5-Methyl-3-pyridinyl)methyl)pyridinium Chloride Trihydrochloride
  • (4aS,4bS,10aR,10bS,11S,12aS)-2',11-Dihydroxy-10a,12a-dimethyl-4,4a,4b,5,6,10a,10b,11,12,12a-decahydro-2H-spiro[chrysene-1,4'-[1,3,2]dioxaphospholane]-2,8(3H)-dione 2'-Oxide (~90%)
  • BB-K31 Hydrochloride (Technical Grade)
  • Itraconazole Mono N-Oxide
  • Flumazenil Carbonyl Chloride Hydrochloride
  • 4-Amino Levamisole Dihydrochloride
  • 70%) Hydrochloride Salt
  • D-myo-Inositol 1,2,3,4,5,6-Hexakisphosphate Sodium Salt Hydrate, Zea mays (&gt
  • cis-Ambroxol Hydrochloride
  • N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine xTFA Salt
  • Validamycin A (&gt
  • α1-24-Adrenocorticotropic-d4 Hormone TFA Salt
  • 1H-Pyrrolo[2,3-c]pyridine-2,3-dione Monohydrate
  • N-Acetyl-S-ethyl-L-cysteine Sodium Salt
  • 80%, Mixture of Diastereomers) Discontinued
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  • 2-Deoxy-D-glucose 6-Phosphate Disodium Salt Hydrate
  • 4-Amino-3,5-dibromo-β-[(1,1-dimethylethyl-d9)amino]benzeneethanol Hydrochloride
  • Mugineic Acid Ammonium Salt
  • Hygromycin B Deuterated (d4 major)
  • 4-Amino-1-((1R,3R,4S,7R)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidin-2(1H)-one
  • TB 500 Trifluoroacetic Salt
  • Amoxycilloic Acid Trisodium Salt (Mixture of Diastereomers) See A634268
  • Polymyxin B1 Formate Salt
  • Allo-3α-tetrahydro Cortisol 3-O-β-D-Glucuronide Sodium Salt-d7 (Major)
  • 90%) Disodium Salt
  • Cefdinir Thiazine Analog Lactone Form (Mixture of Diastereomers)
  • D447570
  • L-Balenine Hydrochloride
  • Abarelix Trifluoroacetate Salt (~90%)
  • 4-Methyl Cannabigerol
  • Lorcaserin Hydrochloride-d4 (&gt
  • Alexamorelin Trifluoroacetic Acid Salt
  • 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone Hydrochloride
  • Isourolithin A 9-Glucuronide Sodium Salt
  • rac-Acetaminophen Mercapturate-d5 (Major)
  • N-Demethyl Trimipramine Hydrochloride
  • (E)-Ceftizoxime Sodium Salt (Mixture of Diastereomers)
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  • (4-Acetyl-L-Serine)Leuprorelin Trifluoroacetic Acid Salt
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  • Acetyl Voclosporin-d4 (Major, ~85%)
  • cis-Aconitic Acid-13C6 Tripotassium Salt
  • 4-Amino-1-[10-[(2-methyl-4-quinolyl)amino]decyl]quinaldinium Iodide Hydriodide
  • p-Cresol Sulfate Potassium Salt-d4
  • Threo-Metaraminol Fumarate Salt
  • Mirabegron O-Glucuronide Sodium Salt
  • Mixture of 1,2’ ,6’ ,3”-Tetra-N-formyl Tobramycin and 3,2’ ,6’ ,3”-tetra-N-formyl Tobramycin (Technical Grade)
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