exo-IWR 1

Product Name: exo-IWR 1
CAS No.: 1127442-87-8
Chemical Name: exo-IWR 1
Synonyms: IWR-1-exo;exo-IWR 1;Inhibitor,exoIWR1,inhibit,Wnt,exo IWR 1;rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide;4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;rel-4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide;Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-
CBNumber: CB12518788
Molecular Formula: C25H19N3O3
Formula Weight: 409.44
MOL File: 1127442-87-8.mol

More

Less

exo-IWR 1 Property

Boiling point:: 643.9±55.0 °C(Predicted)
Density: 1.425±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO
form: Powder
pka: 11.88±0.43(Predicted)
color: Light yellow to green yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 5mg
Price: $67
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 10mg
Price: $128
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 25mg
Price: $297
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 50mg
Price: $525
Updated: 2024/03/01

Tocris

Product number: 3947
Product name: exo-IWR1
Purity: ≥99%(HPLC)
Packaging: 50
Price: $642
Updated: 2021/12/16

More

Less

exo-IWR 1 Chemical Properties,Usage,Production

Uses

exo-IWR-1 is the enantiomer of IWR-1 (I941800). exo-IWR-1 is an SAR anticancer Wnt response inhibitor. Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.

Definition

ChEBI: IWR-1-exo is a dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo. It has a role as an axin stabilizer. It is a dicarboximide and a bridged compound.

exo-IWR 1 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

exo-IWR 1 Suppliers

Canada 1 China 37 India 1 United Kingdom 1 United States 8 Global 48

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

1127442-87-8, exo-IWR 1Related Search:

4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide

exo-IWR 1

IWR-1-exo

rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide

Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-

rel-4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide

Inhibitor,exoIWR1,inhibit,Wnt,exo IWR 1

1127442-87-8