exo-IWR 1

Product Name: exo-IWR 1
CAS No.: 1127442-87-8
Chemical Name: exo-IWR 1
Synonyms: IWR-1-exo;exo-IWR 1;Inhibitor,exoIWR1,inhibit,Wnt,exo IWR 1;rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide;4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;rel-4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide;Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-
CBNumber: CB12518788
Molecular Formula: C25H19N3O3
Formula Weight: 409.44
MOL File: 1127442-87-8.mol

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exo-IWR 1 Property

Boiling point:: 643.9±55.0 °C(Predicted)
Density: 1.425±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO
form: Powder
pka: 11.88±0.43(Predicted)
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 5mg
Price: $67
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 10mg
Price: $128
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 25mg
Price: $297
Updated: 2024/03/01

Cayman Chemical

Product number: 13598
Product name: IWR-1-exo
Purity: ≥98%
Packaging: 50mg
Price: $525
Updated: 2024/03/01

Tocris

Product number: 3947
Product name: exo-IWR1
Purity: ≥99%(HPLC)
Packaging: 50
Price: $642
Updated: 2021/12/16

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exo-IWR 1 Chemical Properties,Usage,Production

Uses

exo-IWR-1 is the enantiomer of IWR-1 (I941800). exo-IWR-1 is an SAR anticancer Wnt response inhibitor. Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.

Definition

ChEBI: IWR-1-exo is a dicarboximide having an exo bridged phthalimide structure, substituted at nitrogen by a 4-(quinolin-8-ylcarbamoyl)benzoyl group. It is a weak axin stabilizer, an analogue of IWR-1-endo. It has a role as an axin stabilizer. It is a dicarboximide and a bridged compound.

exo-IWR 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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exo-IWR 1 Suppliers

Canada 1 China 38 India 1 United Kingdom 1 United States 8 Global 49

EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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InvivoChem

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Aladdin Scientific

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ApexBio Technology

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Cayman Chemical Company

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United States Biological

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1127442-87-8, exo-IWR 1Related Search:

4-[(3aR,4R,7S,7aS-rel)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide

exo-IWR 1

IWR-1-exo

rel-4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-Methano-2H-isoindol-2-yl]-N-8-quinolinylbenzaMide

Benzamide, 4-[(3aR,4R,7S,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-, rel-

rel-4-((3aR,4R,7S,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-N-(quinolin-8-yl)benzamide

Inhibitor,exoIWR1,inhibit,Wnt,exo IWR 1

1127442-87-8