ChemicalBook > CAS DataBase List > 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate

3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate

Product Name
3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate
CAS No.
141064-23-5
Chemical Name
3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate
Synonyms
Lumeron;LY246708 oxalate;Xanomeline oxalate;Xanomeline oxalate salt;LY246708;MEMCOR;LUMERON;3-(3-Hexyloxy-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine oxalate;3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate;3-(Hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole oxalate;3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine ethanedioate (1:1);Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-, ethanedioate (1:1)
CBNumber
CB12518809
Molecular Formula
C14H23N3OS.C2H2O4
Formula Weight
371
MOL File
141064-23-5.mol
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3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate Property

Melting point:
148-150℃
storage temp. 
Desiccate at +4°C
solubility 
DMF: 1.6 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
5.05816
Product name
Xanomeline Oxalate - CAS 141064-23-5 - Calbiochem
Packaging
10mg
Price
$182
Updated
2024/03/01
Cayman Chemical
Product number
10790
Product name
Xanomeline oxalate
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
10790
Product name
Xanomeline oxalate
Purity
≥98%
Packaging
5mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
10790
Product name
Xanomeline oxalate
Purity
≥98%
Packaging
10mg
Price
$160
Updated
2024/03/01
Tocris
Product number
3569
Product name
Xanomelineoxalate
Purity
≥98%(HPLC)
Packaging
10
Price
$195
Updated
2021/12/16
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3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate Chemical Properties,Usage,Production

Description

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline (oxalate), enhance memory function and has utility in treating Alzheimer’s Disease.

Uses

Xanomeline oxalate is a functionally selective mAChR M1 agonist.

storage

Desiccate at +4°C

3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
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MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 18149758185
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sales-cpd@caerulumpharma.com
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China
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Finetech Industry Limited
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027-87465837 19945049750
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027-8777-2287
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sales@finetechnology-ind.com
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LETOPHARM LIMITED
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+86-21-5821 5861
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+86-21-5106 2861
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sales@letopharm.com
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SPIRO PHARMA
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eric_feng1954@126.com
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Hubei Chuangliankangcheng Pharmaceutical Co., Ltd.
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027-65388397 18164111589
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027-65388397
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3321478047@qq.com
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China
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Guangzhou QiYun Biotechnology Co., Ltd.
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020-61288194 61288195
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020-61288700
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505721671@qq.com
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
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141064-23-5, 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalateRelated Search:


  • 3-(3-Hexyloxy-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine oxalate
  • Lumeron
  • LY246708;MEMCOR;LUMERON
  • 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine ethanedioate (1:1)
  • 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridineoxalate
  • Xanomeline oxalate
  • LY246708 oxalate
  • Xanomeline oxalate salt
  • Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-, ethanedioate (1:1)
  • 3-(Hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole oxalate
  • 141064-23-5
  • C14H23N3OSC2H2O4
  • C2H2O4C14H23N3OS
  • 1