ChemicalBook > CAS DataBase List > 10Panx

10Panx

Product Name
10Panx
CAS No.
955091-53-9
Chemical Name
10Panx
Synonyms
10Panx;10Panx, gap junction blocking peptide;Trp Arg Gln Ala Ala Phe Val Asp Ser Tyr;L-Tyrosine, L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-
CBNumber
CB12522406
Molecular Formula
C58H79N15O16
Formula Weight
1242.36
MOL File
955091-53-9.mol
More
Less

10Panx Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥124.2 mg/mL in DMSO; insoluble in EtOH; ≥4.26 mg/mL in H2O with ultrasonic
form 
solid
pka
3.05±0.10(Predicted)
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in water
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2152
Product name
10Panx1 trifluoroacetate salt
Purity
≥98% (HPLC)
Packaging
1MG
Price
$147
Updated
2024/03/01
TRC
Product number
T895400
Product name
L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosineTFASalt
Packaging
1mg
Price
$50
Updated
2021/12/16
TRC
Product number
T895400
Product name
L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosineTFASalt
Packaging
25mg
Price
$305
Updated
2021/12/16
Usbiological
Product number
254341
Product name
10Panx
Packaging
1mg
Price
$389
Updated
2021/12/16
ApexBio Technology
Product number
A2700
Product name
10Panx
Packaging
25mg
Price
$400
Updated
2021/12/16
More
Less

10Panx Chemical Properties,Usage,Production

Uses

L-Tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-L-tyrosine is a connexin mimetic peptide that inhibits pannexin-1 gap junctions.

Biological Activity

10panx is a mimetic inhibitory peptide of panx1, which is a mammalian protein ectopically expressed to function as a hemi-channel, that readily and reversibly inhibits the panx1 currents. 10panx has attracted increasing attention as it allows scientists readily and reliably to examine inhibition of panx1 in cells where efficient and consistent delivery of sirna is highly difficult. according to results of multiple previous studies, 10panx selectively inhibits p2x7r-induced dye uptake without altering other aspects of r2x7r activation and atp-evoked membrane currents, constitutive dye-uptake and hemichannel-like currents that are induced by the overexpression of panx1, and atp-mediated il-1β release.pablo pelegrin and annmarie surprenant. pannexin-1 mediates large pore formation and interleukin-1β release by the atp-gated p2x7 receptor. the embo journal (2006) 25, 5071-5082

storage

Store at -20°C

10Panx Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

10Panx Suppliers

China 38 United States 6 Global 44
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4810
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
6958
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30236
Advantage
58
Binhai gill polypeptide co. LTD
Tel
021-61263389 13524856427
Fax
WeChat630417570
Email
Joetang@glschina.com
Country
China
ProdList
10012
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
Country
China
ProdList
14081
Advantage
58
Shanghai Puluokai Medical Technology Co., LTD
Tel
17269768198
Fax
QQ:1213744847
Email
prochemx@163.com
Country
China
ProdList
613
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Nanjing Yuanpeptide Biotech Co.，Ltd.
Tel
18168071971
Email
support@yuan-peptide.com
Country
China
ProdList
2981
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-88211921 15572296305
Email
sales4@gotopbio.com
Country
China
ProdList
5178
Advantage
58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6628
Advantage
58
Shanghai HongTide Biotechnology Co.,Ltd.
Tel
19961912513
Email
sales@hongtide.com
Country
China
ProdList
4604
Advantage
58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
13770887460
Email
wenxi@jszkhy.com
Country
China
ProdList
1352
Advantage
58
Zhejiang Jiekun Biotechnology Co., Ltd
Tel
0571-88211951 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
4904
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
Taiyuan Bailihengkang Biotechnology Co., Ltd
Tel
19135651983 19135651983
Email
18611134419@163.com
Country
China
ProdList
4416
Advantage
58
Hangzhou Bingochem Co., Ltd.
Tel
0571-8512-5372
Email
sales@bingochem.com
Country
China
ProdList
21669
Advantage
58
Hangzhou Beiputai Biopharmaceutical Co., Ltd
Tel
0571-85350119 15888826472
Email
bptsales@163.com
Country
China
ProdList
3851
Advantage
58
R&D Systems, Inc
Tel
18003437475
Email
rdname@qq.com
Country
CHINA
ProdList
35705
Advantage
58
Changsha MOL Changes Biotechnology Co., Ltd.
Tel
+8619375158599
Email
info@molchanges.com
Country
China
ProdList
5223
Advantage
58
Zhejiang Hangyu API Co., Ltd
Tel
+8617531972939
Email
anna@api-made.com
Country
China
ProdList
2943
Advantage
58
LEAP CHEM CO., LTD.
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
24727
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6705
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Shanghai Benrui Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
john.st@163.com
Country
CHINA
ProdList
1471
Advantage
58
Xiamen Huijia Biological Technology Co., Ltd.
Tel
--
Fax
--
Country
CHINA
ProdList
6973
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58
Shanghai Boyi Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
15800446246@163.com
Country
CHINA
ProdList
5416
Advantage
58
Shanghai Chaoyan Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
471161314@qq.com
Country
CHINA
ProdList
6210
Advantage
58
Beijing Bolide Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
1985563437@qq.com
Country
CHINA
ProdList
6158
Advantage
58
Shanghai Hao Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
shxiyuanbio@163.com
Country
CHINA
ProdList
6906
Advantage
58
Shanghai Yijie Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
SHYIJIEBIO@126.COM
Country
CHINA
ProdList
3510
Advantage
58
Beijing Fubo Biotechnology Co., Ltd.
Tel
--
Fax
--
Email
info@f-biology.com
Country
CHINA
ProdList
6025
Advantage
58

955091-53-9, 10PanxRelated Search:


  • Trp Arg Gln Ala Ala Phe Val Asp Ser Tyr
  • 10Panx
  • L-Tyrosine, L-tryptophyl-L-arginyl-L-glutaminyl-L-alanyl-L-alanyl-L-phenylalanyl-L-valyl-L-α-aspartyl-L-seryl-
  • 10Panx, gap junction blocking peptide
  • 955091-53-9
  • C58H79N15O16
  • peptides