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TP-003

Product Name
TP-003
CAS No.
628690-75-5
Chemical Name
TP-003
Synonyms
TP-003;TP-003/TP003;TP-003|||TP 003|||TP 003|||TP003;4,2'-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]biphenyl-2-carbonitrile;2',4-difluoro-5'-(8-fluoro-7-(2-hydroxypropan-2-yl)imidazo[1,2-a]yridine-3-yl)-[1,1'-biphenyl]-2-carbonitrile;2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile;2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-metyhylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile;[1,1'-Biphenyl]-2-carbonitrile, 2',4-difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]-
CBNumber
CB12526237
Molecular Formula
C23H16F3N3O
Formula Weight
407.39
MOL File
628690-75-5.mol
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TP-003 Property

Density 
1.31
storage temp. 
Store at -20°C
solubility 
<40.74mg/ml in DMSO; <20.37mg/ml in ethanol
form 
Solid
pka
12.04±0.29(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4414
Product name
TP003
Purity
≥98%(HPLC)
Packaging
10
Price
$210
Updated
2021/12/16
Tocris
Product number
4414
Product name
TP003
Purity
≥98%(HPLC)
Packaging
50
Price
$879
Updated
2021/12/16
Usbiological
Product number
256947
Product name
TP 003
Packaging
10mg
Price
$466
Updated
2021/12/16
TRC
Product number
T700568
Product name
TP003
Packaging
50mg
Price
$820
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000361
Product name
TP-003
Purity
95.00%
Packaging
2MG
Price
$213
Updated
2021/12/16
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TP-003 Chemical Properties,Usage,Production

Uses

TP 003 is an α3 subtype selective agonist, which provides a robust anxiolytic-like effect in non-human behavioral models of anxiety.

Biological Activity

TP003 is a potent and subtype selective agonist at α3 GABAA receptors th at exhibits an anxiolytic-like effect in both rodent and non-human primate behavioral models of anxiety. Also it appears th at TP003 have anxiolytic properties but lacks ataxic, hyperphagic, and pronounced sedative effects characteristic of classical benzodiazepines in monkeys. TP003 is consider as α3-over-α1 selective positive allosteric modulator (PAM) at GABBAAR.

storage

Store at +4°C

TP-003 Preparation Products And Raw materials

Raw materials

Preparation Products

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TP-003 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4573
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1925
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30236
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
Fax
qq:1580084073
Email
1580084073@qq.com
Country
China
ProdList
696
Advantage
58
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View Lastest Price from TP-003 manufacturers

Career Henan Chemica Co
Product
TP-003 628690-75-5
Price
US $0.01/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 5kg; 10kg
Release date
2020-10-28

628690-75-5, TP-003Related Search:


  • TP-003
  • 4,2'-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]biphenyl-2-carbonitrile
  • 2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
  • 2',4-difluoro-5'-(8-fluoro-7-(2-hydroxypropan-2-yl)imidazo[1,2-a]yridine-3-yl)-[1,1'-biphenyl]-2-carbonitrile
  • [1,1'-Biphenyl]-2-carbonitrile, 2',4-difluoro-5'-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]-
  • 2',4-Difluoro-5'-[8-fluoro-7-(1-hydroxy-1-metyhylethyl)imidazo[1,2-a]-pyridin-3-yl]-[1,1'-biphenyl]-2-carbonitrile
  • TP-003/TP003
  • TP-003|||TP 003|||TP 003|||TP003
  • 628690-75-5