Synthesis
ChemicalBook > CAS DataBase List > 2H,2H,3H,3H-Perfluoropentanoic acid

2H,2H,3H,3H-Perfluoropentanoic acid

Synthesis
Product Name
2H,2H,3H,3H-Perfluoropentanoic acid
CAS No.
3637-31-8
Chemical Name
2H,2H,3H,3H-Perfluoropentanoic acid
Synonyms
4,4,5,5,5-Pentafluorovaleric acid;2H,2H,3H,3H-Perfluoropentanoic acid;Pentanoic acid, 4,4,5,5,5-pentafluoro-
CBNumber
CB12526530
Molecular Formula
C5H5F5O2
Formula Weight
192.08
MOL File
3637-31-8.mol
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2H,2H,3H,3H-Perfluoropentanoic acid Property

Boiling point:
158.6±35.0 °C(Predicted)
Density 
1.443±0.06 g/cm3(Predicted)
pka
4.11±0.10(Predicted)
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Safety

HS Code 
2915907098
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
P273510
Product name
4,4,5,5,5-PentafluoropentanoicAcid
Packaging
100mg
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
2121-3-X4
Product name
4,4,5,5,5-Pentafluoropentanoic acid
Purity
95%
Packaging
1g
Price
$95
Updated
2021/12/16
Apolloscientific
Product number
PC9660
Product name
4,4,5,5,5-Pentafluoropentanoicacid
Packaging
5g
Price
$100
Updated
2021/12/16
SynQuest Laboratories
Product number
2121-3-X4
Product name
4,4,5,5,5-Pentafluoropentanoic acid
Purity
95%
Packaging
5G
Price
$160
Updated
2021/12/16
Apolloscientific
Product number
PC9660
Product name
4,4,5,5,5-Pentafluoropentanoicacid
Packaging
25g
Price
$390
Updated
2021/12/16
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2H,2H,3H,3H-Perfluoropentanoic acid Chemical Properties,Usage,Production

Synthesis

4,4,5,5,5-Pentaflfluoropentanol (1.8 kg, 10.1 mol), tetraethylammonium hydrogen sulfate (18.1 g, 0.08 mole), and water (10.8 L) were added to a 50 L QVF vessel and heated with stirring to 70 °C. Sodium permanganate monohydrate (2.33 kg, 14.14 mol) was dissolved at 20 °C in water (10.8 L) and transferred to a measure vessel. Aqueous sodium permanganate was added in aliquots (approximately 10% at a time) to the stirred aqueous solution of pentaflfluoropentanol and tetraethylammonium hydrogen sulfate maintaining a temperature of 65−75 °C by the additions of permanganate. The total time taken to add the aqueous permanganate was 2 h 30 min. The reaction was stirred at 70 °C for 4 h when gas chromatography (GC) analysis showed conversion of pentaflfluoropentanol to pentaflfluoropentanoic acid to be complete. The reaction mixture was allowed to cool to ambient temperature overnight and screened through a Celite fifilter aid (500 g) to remove precipitated manganese dioxide. The isolated manganese dioxide was washed with hot water (60 °C, 18 L). The combined aqueous layers were extracted with methyl tert-butyl ether (5.4 L), and the upper organic layer was discarded. The aqueous layer was acidifified with concentrated sulfuric acid (320 mL) to pH 1. The lower organic layer which separated was retained. The aqueous layer was extracted with methyl tert-butyl ether (2 × 5.4 L), and the upper organic layers were combined with the initial, lower organic layer. The combined organic layers were washed with water (5.4 L) and dried with anhydrous sodium sulfate. The organic solvent was removed in vacuo at 50 °C and the residue distilled to give the acid as a pale pink, low-melting solid (1.49 kg, 77%).

Reference: Mahmood, A.; Robinson, G. E.; Powell, L. Org. Proc. Res. Dev. 1999, 3, 363–364.

2H,2H,3H,3H-Perfluoropentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2H,2H,3H,3H-Perfluoropentanoic acid Suppliers

P&M-Invest
Tel
--
Fax
--
Email
notes@fluorine.ru
Country
Russia
ProdList
877
Advantage
66
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View Lastest Price from 2H,2H,3H,3H-Perfluoropentanoic acid manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2H,2H,3H,3H-Perfluoropentanoic acid 3637-31-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09

3637-31-8, 2H,2H,3H,3H-Perfluoropentanoic acidRelated Search:


  • 4,4,5,5,5-Pentafluorovaleric acid
  • 2H,2H,3H,3H-Perfluoropentanoic acid
  • Pentanoic acid, 4,4,5,5,5-pentafluoro-
  • 3637-31-8