FTY720-d4 Hydrochloride
- Product Name
- FTY720-d4 Hydrochloride
- CAS No.
- 1346604-90-7
- Chemical Name
- FTY720-d4 Hydrochloride
- Synonyms
- Fingolimod-d4 HCl;[2H4]-Fingolimod HCl;FTY720-d4 Hydrochloride;FingoliMod-d4 Hydrochloride;[2H4]-Fingolimod Hydrochloride;Fingolimod-d4 HCl (1,3-propane-1,1,3,3-d4-diol);2-AMino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol-d4 Hydrochloride;2-amino-1,1,3,3-tetradeuterio-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
- CBNumber
- CB12545140
- Molecular Formula
- C19H34ClNO2
- Formula Weight
- 343.93176
- MOL File
- 1346604-90-7.mol
FTY720-d4 Hydrochloride Property
- Melting point:
- 105-107°C
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White
N-Bromosuccinimide Price
- Product number
- F805002
- Product name
- Fingolimod-d4Hydrochloride
- Packaging
- 1mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- F805002
- Product name
- Fingolimod-d4Hydrochloride
- Packaging
- 50mg
- Price
- $1705
- Updated
- 2021/12/16
- Product number
- D33275
- Product name
- Fingolimod-d4?HCl
- Packaging
- 25mg
- Price
- $2800
- Updated
- 2021/12/16
FTY720-d4 Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Uses
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. t is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).