ChemicalBook > CAS DataBase List > 5-Methoxy-1H-indole-2-carboxylic acid

5-Methoxy-1H-indole-2-carboxylic acid

Product Name
5-Methoxy-1H-indole-2-carboxylic acid
CAS No.
21778-81-4
Chemical Name
5-Methoxy-1H-indole-2-carboxylic acid
Synonyms
5-methoxy-1H-indole-2-methylaldehyde;5-METHOXY-1H-INDOLE-2-CARBOXALDEHYDE;1H-Indole-2-carboxaldehyde, 5-methoxy-;5-methoxy-1H-indole-2-carbaldehyde - [M85052]
CBNumber
CB12549926
Molecular Formula
C10H9NO2
Formula Weight
175.18
MOL File
21778-81-4.mol
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5-Methoxy-1H-indole-2-carboxylic acid Property

Melting point:
140-141 °C
Boiling point:
375.2±22.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
14.76±0.30(Predicted)
Appearance
Yellow to brown Solid
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Safety

HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC
Product number
M916030
Product name
5-Methoxy-1H-indole-2-carbaldehyde
Packaging
500mg
Price
$330
Updated
2021/12/16
AK Scientific
Product number
7412AD
Product name
5-Methoxy-1H-indole-2-carbaldehyde
Packaging
1g
Price
$353
Updated
2021/12/16
Matrix Scientific
Product number
016206
Product name
5-Methoxy-1H-indole-2-carbaldehyde
Packaging
1g
Price
$225
Updated
2021/12/16
Matrix Scientific
Product number
016206
Product name
5-Methoxy-1H-indole-2-carbaldehyde
Packaging
5g
Price
$775
Updated
2021/12/16
Ambeed
Product number
A213514
Product name
5-Methoxy-1H-indole-2-carbaldehyde
Purity
95%
Packaging
100mg
Price
$59
Updated
2021/12/16
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5-Methoxy-1H-indole-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

21778-77-8

21778-81-4

GENERAL STEPS: A suspension of (5-methoxy-1H-indol-2-yl)methanol (1 mmol) and activated MnO2 (10 mmol) in DMF (30 mL) was stirred at room temperature for 12 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad. The filtrate was concentrated under vacuum and the residue was purified by column chromatography using a solvent mixture of EtOAc-hexane as eluent to give 5-methoxy-1H-indole-2-carbaldehyde.

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 5, p. 2489 - 2512
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 25, p. 6436 - 6440
[3] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 561 - 577
[4] Journal of Medicinal Chemistry, 1987, vol. 30, # 11, p. 2074 - 2080
[5] Journal of Organic Chemistry, 1984, vol. 49, # 17, p. 3195 - 3199

5-Methoxy-1H-indole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methoxy-1H-indole-2-carboxylic acid Suppliers

Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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Cochemical Ltd.
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Aikon International Limited
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View Lastest Price from 5-Methoxy-1H-indole-2-carboxylic acid manufacturers

Career Henan Chemical Co
Product
5-Methoxy-1H-indole-2-carboxylic acid 21778-81-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg ,5kg, 50kg
Release date
2020-01-14

21778-81-4, 5-Methoxy-1H-indole-2-carboxylic acidRelated Search:


  • 5-METHOXY-1H-INDOLE-2-CARBOXALDEHYDE
  • 1H-Indole-2-carboxaldehyde, 5-methoxy-
  • 5-methoxy-1H-indole-2-carbaldehyde - [M85052]
  • 5-methoxy-1H-indole-2-methylaldehyde
  • 21778-81-4