5-Methoxy-1H-indole-2-carboxylic acid
- Product Name
- 5-Methoxy-1H-indole-2-carboxylic acid
- CAS No.
- 21778-81-4
- Chemical Name
- 5-Methoxy-1H-indole-2-carboxylic acid
- Synonyms
- 5-methoxy-1H-indole-2-methylaldehyde;5-METHOXY-1H-INDOLE-2-CARBOXALDEHYDE;1H-Indole-2-carboxaldehyde, 5-methoxy-;5-methoxy-1H-indole-2-carbaldehyde - [M85052]
- CBNumber
- CB12549926
- Molecular Formula
- C10H9NO2
- Formula Weight
- 175.18
- MOL File
- 21778-81-4.mol
5-Methoxy-1H-indole-2-carboxylic acid Property
- Melting point:
- 140-141 °C
- Boiling point:
- 375.2±22.0 °C(Predicted)
- Density
- 1.273±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 14.76±0.30(Predicted)
- Appearance
- Yellow to brown Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
N-Bromosuccinimide Price
- Product number
- M916030
- Product name
- 5-Methoxy-1H-indole-2-carbaldehyde
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- 7412AD
- Product name
- 5-Methoxy-1H-indole-2-carbaldehyde
- Packaging
- 1g
- Price
- $353
- Updated
- 2021/12/16
- Product number
- 016206
- Product name
- 5-Methoxy-1H-indole-2-carbaldehyde
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
- Product number
- 016206
- Product name
- 5-Methoxy-1H-indole-2-carbaldehyde
- Packaging
- 5g
- Price
- $775
- Updated
- 2021/12/16
- Product number
- A213514
- Product name
- 5-Methoxy-1H-indole-2-carbaldehyde
- Purity
- 95%
- Packaging
- 100mg
- Price
- $59
- Updated
- 2021/12/16
5-Methoxy-1H-indole-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
21778-77-8
21778-81-4
GENERAL STEPS: A suspension of (5-methoxy-1H-indol-2-yl)methanol (1 mmol) and activated MnO2 (10 mmol) in DMF (30 mL) was stirred at room temperature for 12 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad. The filtrate was concentrated under vacuum and the residue was purified by column chromatography using a solvent mixture of EtOAc-hexane as eluent to give 5-methoxy-1H-indole-2-carbaldehyde.
References
[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 5, p. 2489 - 2512
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 25, p. 6436 - 6440
[3] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 561 - 577
[4] Journal of Medicinal Chemistry, 1987, vol. 30, # 11, p. 2074 - 2080
[5] Journal of Organic Chemistry, 1984, vol. 49, # 17, p. 3195 - 3199
5-Methoxy-1H-indole-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Methoxy-1H-indole-2-carboxylic acid manufacturers
- Product
- 5-Methoxy-1H-indole-2-carboxylic acid 21778-81-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg ,5kg, 50kg
- Release date
- 2020-01-14