4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester
- Product Name
- 4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester
- CAS No.
- 1242770-50-8
- Chemical Name
- 4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester
- Synonyms
- 4-trifluoroMethyl-trans-beta-styrylboronic acid picol ester;4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester;(E)-4,4,5,5-TetraMethyl-2-(4-(trifluoroMethyl)styryl)-1,3,2-dioxaborolane;4,4,5,5-tetramethyl-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3,2-dioxaborolane;(E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane - [T90493];1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-
- CBNumber
- CB12552647
- Molecular Formula
- C15H18BF3O2
- Formula Weight
- 298.11
- MOL File
- 1242770-50-8.mol
4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester Property
- Melting point:
- 60 °C(Solv: hexane (110-54-3); ethyl acetate (141-78-6))
- Boiling point:
- 282.9±50.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T890120
- Product name
- (E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- T890120
- Product name
- (E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
- Packaging
- 50mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CS-W000371
- Product name
- (E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
- Packaging
- 100mg
- Price
- $64
- Updated
- 2021/12/16
- Product number
- CS-W000371
- Product name
- (E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
- Packaging
- 250mg
- Price
- $102
- Updated
- 2021/12/16
- Product number
- CS-W000371
- Product name
- (E)-4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
- Packaging
- 1g
- Price
- $255
- Updated
- 2021/12/16
4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester Chemical Properties,Usage,Production
Synthesis
705-31-7
25015-63-8
1242770-50-8
SIPrCuCl (C8) (4.9 mg, 5 mol%, 0.01 mmol), tris(tert-butyl)phosphinimine (1b) (2.2 mg, 5 mol%, 0.01 mmol), pinacolborane (1c) (28 mg, 0.22 mmol, 1.1 equiv), 4-ethynyl-α,α,α-trifluorotoluene (1) (0.2 mmol, 1 equiv), and benzene (0.2 mg, 0.1 equiv) were added to oven-dried, screw-capped vials in a nitrogen-ambient glove box with an oxygen and moisture content ≤0.1 ppm. 0.22 mmol, 1.1 equiv), 4-ethynyl-α,α,α-trifluorotoluene (1) (0.2 mmol, 1 equiv), and benzene (2 mL, 0.1 M). The formed reaction mixture was stirred in a glove box for 13 to 15 hours. Subsequently, the dark brown reaction mixture was removed from the glove box and the solvent was removed by rotary evaporator. To the reaction residue, mixed solvent (hexane:ethyl acetate) was added as eluent and stirred at room temperature for about 30 minutes until precipitation was formed. The mixture was further filtered through a short silica gel pad to obtain a colorless filtrate. After removal of the organic solvent under reduced pressure, the target product (E)-4,4,5,5-tetramethyl-2-(4-(trifluoromethyl)styryl)-1,3,2-dioxaborolane was obtained by vacuum drying and did not require further purification.
References
[1] Advanced Synthesis and Catalysis, 2018, vol. 360, # 19, p. 3649 - 3654
[2] Organic Letters, 2017, vol. 19, # 16, p. 4323 - 4326
[3] Tetrahedron Letters, 2017, vol. 58, # 15, p. 1523 - 1527
[4] Chemistry - An Asian Journal, 2013, vol. 8, # 1, p. 50 - 54
[5] Chemistry Letters, 2013, vol. 42, # 10, p. 1128 - 1130
4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester Preparation Products And Raw materials
Raw materials
Preparation Products
4-trifluoroMethyl-trans-beta-styrylboronic acid pinacol ester Suppliers
- Tel
- --
- Fax
- --
- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58